YN482124 Bromisoval 496-67-3

Bromisoval is a hypnotic and sedative of the bromoureide group with anti-inflammatory effects.

YN321504 Scopine 498-45-3

Scopine is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock. Scopine is a tropane alkaloid found in a variety of plants including M and ragora root, Senecio ...

YN360978 Guvacine 498-96-4

Guvacine, an alkaloid found in the nut ofAreca catechu, is a potentGABA uptakpinhibitor. Guvacine inhibitsrat GAT-1,rat GAT-2 and rat GAT-3with IC50 values of 39μM, 58μM and 378μM, respectively.

YN360973 Arecaidine 499-04-7

Arecaidine, a pyridine alkaloid, is a potentGABA uptakeinhibitor. Arecaidine is a substrate of H+-coupled amino acid transporter 1 (PAT1, SLC36A1) and competitively inhibitsL-proline uptake.

YN373074 Nordihydroguaiaretic acid 500-38-9

Nordihydroguaiaretic acid (NDGA) is a phenolic antioxidant found in the leaves and twigs of the evergreen desert shrub, Larrea tridentata (Sesse and Moc. ex DC) Coville (creosote bush). It is a recognized inhibitor of lipoxygena...

YN360882 (+)-Kavain 500-64-1

Kawain is advanced glycation endproduct inhibitors, can increase the mean life span of Caenorhabditis elegans exposed to high glucose. Kawain and dihydromethysticin may enhance the effects of the anxiolytic serotonin-1A agonist ipsapir...

YN322097 Olivetol 500-66-3

Olivetol is a naturally occurring organic compound being a precursor in various syntheses of tetrahydrocannabinol. It acts as a competitive inhibitor of the cannabinoid receptors CB1 and CB2.

YN481993 Beclamide 501-68-8

Beclamide (N-Benzyl-3-chloropropionamide, beta-chlorpropionamide) exhibits sedative and anticonvulsant properties.

YN373299 Nervonic acid 506-37-6

Nervonic acid is a monounsaturated fatty acid important in the biosynthesis of myelin.

YN482437 Gelsemine 509-15-9

Gelsemine has antitumor activity. Gelsemine has anti-oxidative activity. Gelsemine has anti-hyperlipidemic activity. Gelsemine has marked antinociception in inflammatory, neuropathic and bone cancer pains without inducing antinocice...

YN482554 Delsoline 509-18-2

Delsoline, a major alkaloid ofDelphinium anthriscifolium Hance, has both a curare-like effect and a ganglion-blocking effect and is used to relieve muscle tension or hyperkinesia. D.anthriscifolium Hancehas effects of dispelling wi...

YN320094 Spiramide 510-74-7

Spiramide (AMI-193) is a potent and selective antagonist of5-HT2 and dopamine D2 receptor, with Kis of 2nM and 3nM, respectively. Spiramide has >2000-fold selectivity for 5-HT2versus5-HT1C(Ki=4300nM) receptors. Spiramid...

YN380215 Galanthaminone 510-77-0

Galanthaminone (Narwedin) is a competitive and reversible cholinesterase (AChE) inhibitor; is used for the treatment of mild to moderate Alzheimer's disease and various other memory impairments.

YN290073 MAP4343 511-26-2

MAP4343 is the 3-methylether derivative of Pregnenolone. MAP4343 binds in vitro to microtubule-associated protein 2 (MAP2), stimulates the polymerization of tubulin, enhances the extension of neurites and protects neurons agains...

YN320704 Biperiden 514-65-8

Biperiden(KL 373) is an antiparkinsonian agent, which is the selective central M1 cholinoreceptors blocker.

YN380239 Corydaline 518-69-4

Corydaline, an isoquinoline alkaloid, is one of the major active constituents in a new prokinetic botanical agent. Corydaline promotes gastric emptying and small intestinal transit and facilitates gastric accommodation. Corydaline exhib...

YN251708 Citrinin 518-75-2

Citrinin is a mycotoxin which causes contamination in the food and is associated with different toxic effects. Citrinin is usually found together with another nephrotoxic mycotoxin, Ochratoxin A. Citrinin is also reported to possess ...

YN350222 Hesperetin 520-33-2

Hesperetin is a bioflavonoid and, to be more specific, a flavanone.

YN321629 Trimipramine maleate 521-78-8

Trimipramine maleate is a 5-HT receptor antagonist, with pKis of 6.39, 8.10, 4.66 for 5-HT1C, 5-HT2 and  5-HT1A, respectively.

YN1730113 Tetrahydroberberine 522-97-4

Tetrahydroberberine is an isoquinoline alkaloid with micromolar affinity for dopamine D2 (antagonist, pKi = 6.08) and 5-HT1A (agonist, pKi = 5.38) receptors but moderate to no affinity for other relevant serotonin receptors.