YN373264 Curcumenol 19431-84-6

Curcumenol, a sesquiterpene isolated from Curcuma zedoaria, is known to possess a variety of health and medicinal values which includes neuroprotection, anti-inflammatory, anti-tumor and hepatoprotective activities. It inhibits NF-κB...

YN483326 2-O-Acetyl-20-hydroxyecdyson... 19536-25-5

2-O-Acetyl-20-hydroxyecdysone, an ecdysterones in insects and terrestrial plants, inhibits amyloid-β42(Aβ42)-induced cytotoxicity. 2-O-Acetyl-20-hydroxyecdysone could decrease Aβ oligomer formation through promotion of fibrogenes...

YN330608 1,3-Dicaffeoylquinic acid 19870-46-3

1,3-Dicaffeoylquinic acid is a caffeoylquinic acid derivative that exhibits antioxidant activity and radical scavenging activity.

YN482707 29-Nor-20-oxolupeol 19891-85-1

29-Nor-20-oxolupeol, extracted fromImpatiens basamina, reduces NO levels in LPS-activated murine microglial cells with an IC50 of 44.21 µM.

YN1730043 SKF 38393 hydrobromide 20012-10-6

SKF 38393 hydrobromide is a selective agonist of thedopamine D1 receptor (D1DR)with an IC50 of 110nM.

YN481945 Idramantone 20098-14-0

Idramantone (Kemantane), an Adamantane derivative, is an immunostimulant.

YN380234 Tenuifolin 20183-47-5

Tenuifolin has no inherent toxicity to either the transfected or wild type cells at the effective concentrations, it inhibits amyloid-β secretion in vitro.

YN483510 Magnolioside 20186-29-2

Magnolioside, isolated fromAngelica gigas Nakai(Umbelliferae), exhibits significant neuroprotective activities against glutamate-induced toxicity.

YN320645 6-Alpha Naloxol 20410-95-1

6-Alpha Naloxol(Alpha-Naloxol) is an opioid antagonist closely related to naloxone; a human metabolite of naloxone. IC50 value:

YN360938 Talatisamine 20501-56-8

Talatisamine (120 μM) and TEA (5mM) inhibits the enhanced I(K) caused by Aβ40 oligomers, attenuates cytotoxicity of Aβ oligomers by restoring cell viability and suppressing K(+) loss related apoptotic response. Talatisamine c...

YN370648 LysoPC(14:0/0:0) 20559-16-4

LysoPC(14:0/0:0) is a lysophospholipid (LyP). It is a monoglycerophospholipid in which a phosphorylcholine moiety occupies a glycerol substitution site. LysoPC(14:0/0:0) has potent antispasmodic effect.

YN373183 Methysticin 20697-20-5

Methysticin is a major kavalactone in kava extract to induceCYP1A1.

YN380225 Saikosaponin C 20736-08-7

Saikosaponin C is a bioactive component found inradix bupleuri, targetsamyloid beta and tauin Alzheimer's disease. Saikosaponin C inhibits the secretion of both Aβ1-40 and Aβ1-42, and suppresses abnormal tau phosphorylation, bu...

YN483585 Vitamin B15 20858-86-0

Vitamin B15 (Pangamic Acid) is a natural, ubiquitously in plant seeds substance and can used be as an agent stimulating cellular respiration. Vitamin B15 contains D-gluconodimethyl amino acetic acid. Vitamin B15 is also a immune-...

YN482351 Orcinol glucoside 21082-33-7

Orcinol glucoside (OG) is an active constituent isolated fromRhizoma Curculiginis, with antidepressant effects. Orcinol glucoside facilitates the shift of MSC fate to osteoblast and prevents adipogenesis via Wnt/β-catenin signa...

YN380268 Lycoramine 21133-52-8

Lycoramine, a dihydro-derivative of galanthamine, is isolated fromLycoris radiate. Lycoramine is a potentacetylcholinesterase (AChE)inhibitor.

YN360339 (S)-Willardiine 21416-43-3

(S)-Willardiine is a potent agonist of AMPA/kainate receptors with EC50 of 44.8 uM.

YN480339 Picrotin 21416-53-5

Picrotin is an inhibitor ofglycine receptors (GlyRs)which blocks α2 GlyR, α1 GlyR and α3 GlyR.

YN321602 Lofexidine hydrochloride 21498-08-8

Lofexidine (hydrochloride) is a selectiveα2-receptoragonist, commonly used to alleviate the physical symptoms of heroin and other types of opioid withdrawal.

YN321409 Mianserin hydrochloride 21535-47-7

Mianserin is an potent antagonist of H1 histamine receptor and 5-HT serotonin receptors, used for the treatment of depression.