YN360412 Rivanicline 15585-43-0

Rivanicline (RJR-2403; (E)-Metanicotine) is aneuronal nicotinic receptoragonist, showing high selectivity for the α4β2 subtype (Ki=26nM); > 1,000 fold selectivity than α7 receptors(Ki= 36000nM).

YN1730099 Molindone hydrochloride 15622-65-8

Molindone hydrochloride is the hydrochloride salt form of molindone, a conventional antipsychotic used in the therapy of schizophrenia. It is a dopamine D2/D5 receptor antagonist.

YN480242 Ryanodine 15662-33-6

Ryanodine is a cell permeantryanodine receptormodulator. Ryanodine can either stimulate or inhibit Ryanodine-mediated Ca2+release depending on its concentrations. Poisonous diterpenoid found inRyania speciosa.

YN1730100 Sulpiride 15676-16-1

Sulpiride is a dopamine D2-receptor antagonist. It has been used therapeutically as an antidepressant, antipsychotic, and as a digestive aid.

YN484192 Pyrrolifene 15686-97-2

Pyrrolifene is an analgesic with anti-inflammatory effect.

YN484393 β-N-methylamino-L-alanine h... 16012-55-8

β-N-methylamino-L-alanine hydrochloride (BMAA hydrochloride) is a neurotoxin produced by cyanobacteria. β-N-methylamino-L-alanine hydrochloride could cause amyotrophic lateral sclerosis (ALS) and possibly other neurodegenera...

YN250552 Levamisole hydrochloride 16595-80-5

(-)-Tetramisole is an inhibitor of alkaline phosphatase, used as an anthelmintic.

YN480721 MTSEA hydrobromide 16599-33-0

MTSEA hydrobromide is a sulfhydryl-reactive compound that modifies free cysteine residues to produce a positively charged side chain approximately the size of lysine.

YN330550 Asiaticoside 16830-15-2

Asiaticoside, the major active principle of Centella asiatica, prevents ultraviolet A-dependent photoaging by suppressing ultraviolet A-induced reactive oxygen species production. It also decreases DNA binding by MITF.

YN360933 Reserpine hydrochloride 16994-56-2

Reserpine hydrochloride is an inhibitor of thevesicular monoamine transporter 2(VMAT2).

YN480343 Dihydroactinidiolide 17092-92-1

Dihydroactinidiolide, existing in plant leaves and fruits, is a potent plant growth inhibitor, a regulator of gene expression and is responsible for photo acclimation in Arabidopsis. Dihydroactinidiolide has antioxidant activity, ant...

YN380174 Clomipramine hydrochloride 17321-77-6

Clomipramine HCl is a hydrochloride salt of clomipramine which is a serotonin transporter (SERT), norepinephrine transporter (NET) dopamine transporter (DAT) blocker with Ki of 0.14, 54 and 3 nM, respectively.

YN480768 Theogallin 17365-11-6

Theogallin (3-Galloylquinic acid) is an active ingredient in decaffeinated green tea extract. Theogallin has antidepressive and cognition enhancing effect.

YN321263 BGC20-761 17375-63-2

BGC20-761 is a selecvtive5-HT6 and dopamine receptorantagonist (human receptorKivalues: 5-HT6 (20nM), 5-HT2A (69nM), D2 (140nM). BGC20-761, can enhance long-term memory. BGC20-761 has potential utility as an antipsychot...

YN373258 Tomatine 17406-45-0

Tomatine is a glycoalkaloid, found in the tomato plant (Lycopersicon esculentumMill.). Tomatine elicits neurotoxicity in RIP1 kinase and caspase-independent manner. Tomatine promotes the upregulation of nuclear apoptosis inducing ...

YN1730050 Dicarbine 17411-19-7

Dicarbine blocksdopamine receptorsin various brain parts and prevents the depression of the conditioned defence reflexes caused by stimulation of the mesencephalic portion of the reticular formation. Dicarbine could be used in the schiz...

YN360873 Picrotoxinin 17617-45-7

Picrotoxinin, a potent convulsant, is achloride channelblocker. Picrotoxinin is a noncompetitiveGABAAreceptorantagonist, which negatively modulates the action of GABA on GABAAreceptors.

YN482687 Nicotiflorin 17650-84-9

Nicotiflorin is a flavonoid glycoside extracted from a traditional Chinese medicineFlos Carthami. Nicotiflorin shows potentantiglycationactivity and neuroprotection effects.

YN321746 Racanisodamine 17659-49-3

Raceanisodamine is the active ingredient of Chinese herbal extracts that has vasoactive activity used to treat acute disseminated intravascular coagulation in patients in bacteremic shock.

YN373263 Neoruscogenin 17676-33-4

Neoruscogenin, a member of the steroidal sapogenin family, is a bioavailable, potent, and high-affinity agonist of the nuclear receptorRORα (NR1F1).