YN380204 Tranylcypromine hemisulfate 13492-01-8

Tranylcypromine hemisulfate (dl-Tranylcypromine hemisulfate) is an irreversible, nonselectivemonoamine oxidase (MAO)inhibitor used in the treatment of depression. Tranylcypromine hemisulfate is also alysine-specific demethylase 1 (LS...

YN321594 Pindolol 13523-86-9

Pindolol (LB-46) is a nonselective β-blocker with partial beta-adrenergic receptor agonist activity, also functions as a 5-HT1A receptor weak partial antagonist (Ki=33nM).

YN360160 BNC210 13589-06-5

BNC210 (H-Ile-Trp-OH, IW-2143) is a negative allosteric modulator of alpha-7 nicotinic acetylcholine receptor (α7 nAChR).

YN481924 Amoxapine 14028-44-5

Amoxapine is a tricyclic dibenzoxazepine (an N-aryl piperazine) which acts similarly to several other tricyclic antidepressants, amoxapine inhibits GLYT2a transport activity with IC50 of 92 μM.

YN373195 Royal Jelly acid 14113-05-4

Royal jelly acid is the principal lipid component in royal jelly which is the food for queen and larvae honeybees. It is involved in several treatment processes of autoimmune and inflammatory diseases, including inhibition of lipopolysacc...

YN320062 4-Hydroxypropranolol hydrochl... 14133-90-5

4-Hydroxypropranolol hydrochlorid is an active metabolite of Propranolol. 4-Hydroxypropranolol hydrochlorid is of comparable potency to Propranolol. 4-Hydroxypropranolol hydrochlorid inhibitsβ1- and β2-adrenergic receptorswithpA2v...

YN280136 Diosgenin glucoside 14144-06-0

Diosgenin glucoside and other synthetic glycosides with similar activities may be of use in the management of hypercholesterolemia and atherosclerosis. Significant inhibition of Diosgenin glucoside synthesis and stimulation of solasodin...

YN330567 20(S)-Ginsenoside Rg3 14197-60-5

20(S)-Ginsenoside Rg3 is the main component of Red ginseng. Ginsenoside Rg3 inhibitsNa+ and hKv1.4channel with IC50s of 32.2±4.5 and 32.6±2.2μM, respectively. 20(S)-Ginsenoside Rg3 also inhibitsAβlevels,NF-κBactivit...

YN360967 Domoic acid 14277-97-5

Domoic acid ((-)-Domoic acid; L-Domoic acid) is an excitatory neurotransmitter isolated from a form of marine vegetation,Nitzschia pungens. Domoic acid produces neurotoxic effect through activatingkainate receptor.

YN482869 Cnidilin 14348-22-2

Cnidilin (Knidilin) is isolated from the root ofAngelica dahurica.

YN374026 4-Bromo-3-hydroxybenzoic acid 14348-38-0

4-bromo-3-hydroxybenzoic acid is a potent inhibitor of the enzyme histidine decarboxylase with resultant inhibition of histamine formation in mammals.

YN371096 Mebeverine alcohol 14367-47-6

Mebeverine alcohol is a metabolite of Mebeverine, which is a musculotropic antispasmodic drug.

YN480038 Cinperene 14796-24-8

Cinperene is an atropine-like drug which can block pilocarpine-induced lacrimation and salivation.

YN330439 Bismuth Subsalicylate 14882-18-9

Bismuth Subsalicylate is the active ingredient in Pepto-Bismol and inhibits prostagl and in G/H Synthase 1/2.

YN481811 Benserazide hydrochloride 14919-77-8

Benserazide HCl is a peripherally-acting aromatic L-amino acid decarboxylase (AAAD) or DOPA decarboxylase inhibitor.

YN321446 Clemastine fumarate 14976-57-9

Clemastine Fumarate (Clemastine) is a selective histamine H1 receptor antagonist with IC50 of 3 nM.

YN310348 Ginkgolide C 15291-76-6

Ginkgolide C, isolated from Ginkgo biloba leaves, is a flavone reported to have multiple biological functions, from decreased platelet aggregation to ameliorating Alzheimer disease.

YN320898 3,3'-Difluorobenzaldazine 15332-10-2

3,3'-Difluorobenzaldazine (DFB) is a selective positive allosteric modulator of mGluR5. 3,3'-Difluorobenzaldazine potentiates 3- to 6-fold action for mGlu5 agonists (Glutamate, Quisqualate, and 3,5-Dihydroxyphenylglycine), with...

YN360786 Pancuronium dibromide 15500-66-0

Pancuronium dibromide is a competitive nicotinic acetylcholine receptor antagonist, used as a muscle relaxant.

YN321391 Pizotifen 15574-96-6

Pizotifen (Pizotyline, BC-105) is a potent antagonist of 5-Hydroxytryptamine (5-HT, Serotonin) 5-HT2 receptor with a high affinity for 5-HT1C binding site.