YN380129 ARN2966 102212-26-0

ARN2966 is a potent post-transcriptional modulator of APP expression; reduces expression of APP with resultant lower production of Aβ. This potent post-transcriptional modulation of APP expression differs from other mechanis...

YN320139 Otenzepad 102394-31-0

Otenzepad (AF-DX 116) is a selective and competitiveM2 muscarinic acetylcholine receptorantagonist, with IC50 values of 640nM and 386nM for rabbit peripheral lung and rat heart, respectively.

YN380120 (-)-Huperzine A 102518-79-6

(-)-Huperzine A is a potent, highly specific and reversible inhibitor of acetylcholinesterase (AChE) with Ki of 7 nM, exhibiting 200-fold more selectivity for G4 AChE over G1 AChE. Also acts as an NMDA receptor antagonis...

YN321390 Levetiracetam 102767-28-2

Levetiracetam is an anticonvulsant medication used to treat epilepsy.

YN483841 [D-p-Cl-Phe6,Leu17]-VIP 102805-45-8

[D-p-Cl-Phe6,Leu17]-VIP is a competitive and selective antagonist ofvasoactive intestinal peptide (VIP) receptor, with theIC50 of 125.8nM. [D-p-Cl-Phe6,Leu17]-VIP has no activity on glucagon, secretin or GRF recepto...

YN321884 Kinetensin 103131-69-7

Kinetensin is aneurotensin-like peptide isolated from pepsin-treated human plasma.

YN481836 Taltirelin 103300-74-9

Taltirelin (TA0910) is a superagonist atthyrotropin-releasing hormone receptor (TRH-R)with an IC50 of 910nM and EC50of 36nM for stimulating an increase in cytosolic Ca2+concentration (Ca2+release).

YN330014 D-α-Hydroxyglutaric acid di... 103404-90-6

Disodium (R)-2-Hydroxyglutarate is a competitive inhibitor of α-ketoglutarate-dependent dioxygenases with Ki of 0.628 mM.

YN321915 CTOP 103429-31-8

CTOP is a peptide that acts as aμ-opioid receptorantagonist.

YN321920 CTAP 103429-32-9

CTAP is a potent, highly selective, and brain penetrantμ opioid receptorantagonist (IC50=3.5nM) and displays over 1200-fold selectivity over δ opioid (IC50=4500nM) and somatostatin receptors. CTAP can be used for the s...

YN380244 Huperzine B 103548-82-9

Huperzine-B is a efficient inhibitor of human brain AChE. Huperzine-B can enhance ognitive and protect neuro, may be potentially new drug candidates for Alzheimer's disease therapy.

YN321393 Sumatriptan succinate 103628-48-4

Sumatriptan Succinate is a triptan sulfa drug containing a sulfonamide group for the treatment of migraine headaches.

YN321366 Ondansetron hydrochloride dih... 103639-04-9

Ondansetron is a highly specific and selective serotonin 5-HT3 receptor antagonist (Ki=6.16 nM), with low affinity for dopamine receptors.

YN380095 Lazabemide hydrochloride 103878-83-7

Lazabemide hydrochloride (Ro 19-6327 hydrochloride) is a selective, reversible inhibitor ofmonoamine oxidase B (MAO-B)(IC50=0.03μM) but less active for MAO-A (IC50>100μM). Lazabemide  inhibits monoamine uptake at high c...

YN380094 Lazabemide 103878-84-8

Lazabemide is a reversible and selective inhibitor of monoamine oxidase B (MAO-B) with Ki value of 7.9 nM.

YN360446 Sepimostat 103926-64-3

Sepimostat exhibits neuroprotective activity viaNR2B N-methyl-D-aspartate receptorantagonism at the Ifenprodil-binding site of the NR2B subunit. Sepimostat inhibits the Ifenprodil binding with a Kivalue of 27.7 µM.

YN483972 Calmodulin Binding Peptide ... 104041-80-7

Calmodulin Binding Peptide 1 is a high affinity (pM) CaM-binding peptide derived from smooth muscle myosin light-chain kinase (MLCK peptide), which strongly inhibits IP3-induced Ca2+release.

YN320585 Atipamezole 104054-27-5

Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug.

YN320584 Atipamezole hydrochloride 104075-48-1

Atipamezole is a synthetic α2 adrenergic receptor antagonist. It has also been researched in humans as a potential anti-Parkinsonian drug. Atipamezole hydrochloride is hydrochloride form of atipamezole.

YN360140 Gabazine 104104-50-9

Gabazine is a selective and competitive antagonist ofGABAAreceptor, with an IC50 of ~0.2μM for GABA receptor.