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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN484028 Phe-Met-Arg-Phe Like Pep... 98495-35-3

    Phe-Met-Arg-Phe Like Peptide, Snail Helix aspersa is a FMRF-like peptide from visceral and somatic muscles of thesnail Helix aspersa. FMRF (Phe-Met-Arg-Phe) is a neuropeptide peptide consisting of 4 amino acid residue...

  • YN360804 Ropivacaine hydrochloride 98717-15-8

    Ropivacaine hydrochloride is a potentsodium channelblocker and blocks impulse conduction via reversible inhibition ofsodium ion influxin nerve fibrese. Ropivacaine is also an inhibitor of K2P(two-pore domain potassium channel)TREK...

  • YN481395 Reboxetine mesylate 98769-84-7

    Reboxetine is a norepinephrine reuptake inhibitor with Ki of 8.2 nM.

  • YN320254 Proglumide sodium 99247-33-3

    Proglumide sodium is a nonpeptide and orally activecholecystokinin (CCK)-A/B receptorsantagonist. Proglumide sodium selective blocksCCK’s effects in the central nervous system (CNS). Proglumide sodium has ability to inhibit...

  • YN320262 SKF-83566 99295-33-7

    SKF-83566 is a potent, blood-brain permeable and orally activeD1-like dopamine receptor (D1DR)antagonist and a weaker competitive antagonist at the vascular 5-HT2receptor (Ki=11nM). SKF-83566 is a competitive DAT (dopa...

  • YN380169 Venlafaxine hydrochloride 99300-78-4

    Venlafaxine HCl is an arylalkanolamine serotonin-norepinephrine reuptake inhibitor (SNRI), used to treat major depressive disorder (MDD), generalised anxiety disorder (GAD), panic disorder and social phobia.

  • YN482287 EGTA-AM 99590-86-0

    EGTA-​AM is a membrane permeable form of EGTA, can be passively loaded into cells to generate intracellular EGTA; EGTA-​AM is also a Ca2+chelator with slow chelating dynamics.

  • YN360171 Rilmazafone 99593-25-6

    Rilmazafone is a benzodiazepine (omega) lig and with sedative and hypnotic effects.

  • YN321365 Ondansetron hydrochloride 99614-01-4

    Ondansetron is a serotonin 5-HT3 receptor antagonist, used to prevent nausea and vomiting caused by cancer chemotherapy, and radiation therapy.

  • YN321367 Ondansetron 99614-02-5

    Ondansetron(GR 38032; SN 307) is a serotonin 5-HT3 receptor antagonist used mainly as anantiemetic (to treat nausea and vomiting), often following chemotherapy.

  • YN321304 Rotigotine 99755-59-6

    Rotigotine is a dopamine receptor agonist, used in the treatment of Parkinson's disease and restless legs syndrome.

  • YN484033 Calcitonin Gene Related Pe... 99889-63-1

    Calcitonin Gene Related Peptide (CGRP) II, rat is a neuropeptide with 37 amino acid.

  • YN380229 Rosiridin 100462-37-1

    Rosiridin, which is isolated fromRhodiola roseaL., inhibitsMAO A and MAO Bwith potential beneficial effect in depression and senile dementia. Rosiridin shows an inhibition of 83.8% against MAO B at 10μM (pIC50=5.38).

  • YN1730022 CY 208-243 100999-26-6

    CY 208-243 is a selectivedopamine D1 receptoragonist which exhibits antiparkinsonian activity.

  • YN380165 Milnacipran hydrochloride 101152-94-7

    Milnacipran inhibits both norepinephrine transporter (NET) and norepinephrine transporter (SERT) with IC50 of 77 nM and 420 nM, respectively.

  • YN380023 Phenserine 101246-66-6

    Phenserine ((-)-Eseroline phenylcarbamate) is a derivative of Physostigmine and is a potent, noncompetitive, long-acting and selectiveAChEinhibitor. Phenserine reducesβ-amyloid precursor protein (APP) and β-amyloid peptide (...

  • YN360834 Lomerizine dihydrochloride 101477-54-7

    Lomerizine dihydrochloride is a relatively new L- and T-type calcium channel blocker used in the treatment of migraine.

  • YN321820 Neurokinin B TFA 101536-55-4

    Neurokinin B TFA belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.

  • YN1730091 Talipexole 101626-70-4

    Talipexole (B-HT920) is a dopamine agonist that has been proposed as an antiparkinsonian agent.

  • YN320973 (Rac)-Rotigotine hydrochlori... 102120-99-0

    (Rac)-Rotigotine hydrochloride is a racemate of Rotigotine. Rotigotine is a full agonist ofdopamine receptor, a partial agonist of the5-HT1A receptor, and an antagonist of theα2B-adrenergic receptor, with Kis of 0.71 nM, 4-15 ...

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