YN1730004 CGP 25454A 104391-26-6

CGP 25454A is a novel and selective presynaptic dopamine autoreceptor antagonist. In vitro: CGP 25454A increase the field-stimulated [3H]- and [14C]-overflow from rat striatal slices preloaded with [3H]dopamine and [14C]...

YN480019 Ipenoxazone 104454-71-9

Ipenoxazone is a potent and centrally acting muscle relaxant.

YN480771 EC23 104561-41-3

EC23 (AGN 190205) is a stable synthetic retinoid analogue and induces neuronal differentiation.

YN1730075 Pramipexole dihydrochloride 104632-25-9

Pramipexole dihydrochloride is a dopamine agonist of the non-ergoline class indicated for treating Parkinson's disease (PD) and restless legs syndrome (RLS) with Ki values of 3.9 nM, 2.2 nM, 0.5 nM and 5.1 nM for D2S receptor,...

YN1730095 Pramipexole 104632-26-0

Pramipexole is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively.

YN1730076 Dexpramipexole dihydrochlorid... 104632-27-1

Dexpramipexole dihydrochloride ((R)-Pramipexole dihydrochloride) is a neuroprotective agent and weak non-ergoline dopamine agonist.

YN1730077 Dexpramipexole 104632-28-2

Dexpramipexole(KNS-760704), also known as R-(+)-Pramipexole, is a neuroprotective agent and weak non-ergoline dopamine Dexpramipexole has been found to have neuroprotective effects and is being investigated for treatment of amyot...

YN480626 Eslicarbazepine 104746-04-5

Eslicarbazepine is an oral anticonvulsant indicated for the adjunctive treatment of partial seizures.

YN360225 NF023 hexasodium 104869-31-0

NF023 hexasodium is a selective and competitiveP2X1receptorantagonist, with IC50 values of 0.21μM, 28.9μM, > 50μM and > 100μM for human P2X1, P2X3, P2X2, and P2X4-mediated responses respectively.

YN380248 Aloeresin D 105317-67-7

Aloeresin D is a chromone glycoside isolated fromAloe vera, inhibits β-Secretase (BACE1) activity, with an IC50 of 39μM.

YN380098 RS 8359 105365-76-2

RS 8359 is a selective and reversibleMAO-Ainhibitor, with antidepressant activity.

YN361098 Linopirdine 105431-72-9

Linopirdine (DuP 996) is an orally active, selectiveM-type K+current (IM; Kv7; KCNQ Channels)inhibitor with an IC50 of 2.4μM. Linopirdine is aTRPV1agonist. Linopirdine, a putative cognition enhancing drug, increases a...

YN321372 Tropisetron Hydrochloride 105826-92-4

Tropisetron HCl is a potent and selective 5-HT3 receptor antagonist and α7-nicotinic receptor agonist, used to treat nausea and vomiting following chemotherapy.

YN360641 Radafaxine hydrochloride 106083-71-0

Radafaxine hydrochloride (GW-353162A) is aDAT (dopamine transporter) and NET(norepinephrine transporter)transporters inhibitor, and nAChR family modulator. Radafaxine hydrochloride (GW-353162A) is a potent metabolite of b...

YN321800 Senktide 106128-89-6

Senktide is a tachykininNK3receptoragonist.

YN321553 Tamsulosin 106133-20-4

Tamsulosin is a selective α1 receptor antagonist that has preferential selectivity for the α1A receptor in the prostate versus the α1B receptor in the blood vessels.

YN320563 Thioperamide 106243-16-7

Thioperamide (MR-12842) is a potent, orally available, brain penetrant and selectiveH3 receptorantagonist with a Ki of 4.3nM for inhibition of [3H]histamine release. Thioperamide inhibits [3H]histamine synthesis with a Ki of 31n...

YN320410 Risperidone 106266-06-2

Risperidone is a mutil-targeted antagonist for dopamine, serotonin, adrenergic and histamine receptors, used to treat schizophrenia and bipolar disorder.

YN481748 Rufinamide 106308-44-5

Rufinamide is a voltage-gated sodium channel blocker, used an anticonvulsant medication.

YN361022 ω-Conotoxin GVIA 106375-28-4

ω-Conotoxin GVIA is an inhibitor of the N-typeCa2+channel.