PIM-447 dihydrochloride
Cat. No. :YN340216
CAS No. :1820565-69-2
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order@ubiochem.com| Product Name: | PIM-447 dihydrochloride |
| CAS NO.: | 1820565-69-2 |
| Chemical Name: | |
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| Molecular Weight: | 513.38 |
| Molecular Formula: | C₂₄H₂₅Cl₂F₃N₄O |
| SMILES: | O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=C([C@H]4C[C@@H](N)C[C@@H](C)C4)C=CN=C3.Cl.Cl |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | PIM447 dihydrochloride (LGH447 dihydrochloride) is a potent, orally available, and selective pan-PIMkinase inhibitor, with Ki values of 6, 18, and 9 pM for PIM1, PIM2, and PIM3, respectively. PIM447 dihydrochloride displays dual antimyeloma and bone-protective effects. PIM447 dihydrochloride inducesapoptosis. |
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