SGI-1776
Cat. No. :YN340129
CAS No. :1025065-69-3
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order@ubiochem.com| Product Name: | SGI-1776 |
| CAS NO.: | 1025065-69-3 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 405.42 |
| Molecular Formula: | C₂₀H₂₂F₃N₅O |
| SMILES: | CN1CCC(CC1)CNC2=NN3C(C=C2)=NC=C3C4=CC=CC(OC(F)(F)F)=C4 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SGI-1776 free base is a novel ATP competitive inhibitor of Pim1 with IC50 of 7 nM in a cell-free assay, 50- and 10-fold selective versus Pim2 and Pim3, also potent to Flt3 and haspin. Phase 1. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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