CK2/ERK8-IN-1
Cat. No. :YN340142
CAS No. :1085822-09-8
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Product Name: | CK2/ERK8-IN-1 |
CAS NO.: | 1085822-09-8 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 534.82 |
Molecular Formula: | C₁₁H₉Br₄N₃O₂ |
SMILES: | O=C(O)CN1C2=C(Br)C(Br)=C(Br)C(Br)=C2N=C1N(C)C |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | CK2/ERK8-IN-1 is a dualcasein kinase 2 (CK2)(Kiof 0.25 µM) and ERK8(MAPK15, ERK7) inhibitor with IC50s of 0.50μM. CK2/ERK8-IN-1 also binds toPIM1,HIPK2(homeodomain-interacting protein kinase 2), and DYRK1Awith Kis of 8.65 µM, 15.25 µM, and 11.9 µM, respectively. CK2/ERK8-IN-1 haspro-apoptoticefficacy. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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