INCB053914 phosphate
Cat. No. :YN340028
CAS No. :2088852-47-3
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5mg
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Product Name: | INCB053914 phosphate |
CAS NO.: | 2088852-47-3 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 611.51 |
Molecular Formula: | C₂₆H₂₉F₃N₅O₇P |
SMILES: | O=C(C1=NC(C2=C(F)C=CC=C2F)=C(F)C=C1)NC3=CN=C4C(CC[C@H]4O)=C3N5C[C@@H](N)[C@H](O)[C@@H](C)C5.OP(O)(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | INCB053914 phosphate is an orally active, ATP-competitive pan-PIM kinaseinhibitor with IC50s of 0.24nM, 30nM, 0.12nM for PIM1, PIM2, PIM3, respectively. INCB053914 phosphate has broad anti-proliferative activity against a variety of hematologic tumor cell lines. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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