AV-412
Cat. No. :YN340045
CAS No. :451493-31-5
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Product Name: | AV-412 |
CAS NO.: | 451493-31-5 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 851.41 |
Molecular Formula: | C₄₁H₄₄ClFN₆O₇S₂ |
SMILES: | O=S(C1=CC=C(C)C=C1)(O)=O.C=CC(NC2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2C#CC(N5CCN(C)CC5)(C)C)=O.O=S(C6=CC=C(C)C=C6)(O)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | AV-412 (MP412) is anEGFRinhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively. |
IC50&Target: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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