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AV-412

Cat. No. :YN340045

  • CAS No. :451493-31-5

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    • Products Infomation
    • Biological Activity
    • Reference
    • Product Name:AV-412
      CAS NO.:451493-31-5
      Chemical Name:
      Synonyms:
      Molecular Weight:851.41
      Molecular Formula:C₄₁H₄₄ClFN₆O₇S₂
      SMILES:O=S(C1=CC=C(C)C=C1)(O)=O.C=CC(NC2=CC3=C(NC4=CC=C(F)C(Cl)=C4)N=CN=C3C=C2C#CC(N5CCN(C)CC5)(C)C)=O.O=S(C6=CC=C(C)C=C6)(O)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:AV-412 (MP412) is anEGFRinhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively.
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