AV-412 free base
Cat. No. :YN340046
CAS No. :451492-95-8
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Product Name: | AV-412 free base |
CAS NO.: | 451492-95-8 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 507.00 |
Molecular Formula: | C₂₇H₂₈ClFN₆O |
SMILES: | O=C(C=C)NC1=CC2=C(NC3=CC=C(C(Cl)=C3)F)N=CN=C2C=C1C#CC(C)(C)N(CC4)CCN4C |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | AV-412 free base (MP-412 free base) is an EGFRinhibitor with IC50s of 0.75, 0.5, 0.79, 2.3, 19nM for EGFR, EGFRL858R, EGFRT790M, EGFRL858R/T790M and ErbB2, respectively. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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