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BDTX-189

Cat. No. :YN340146

  • CAS No. :2414572-47-5

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    • Products Infomation
    • Biological Activity
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    • Product Name:BDTX-189
      CAS NO.:2414572-47-5
      Chemical Name:
      Synonyms:
      Molecular Weight:561.03
      Molecular Formula:C₂₉H₂₉ClN₆O₄
      SMILES:C=CC(NC1=CC2=C(NC3=CC=C(OCC4=NC=CC=C4)C(Cl)=C3)N=CN=C2C=C1OCCN5CCOCC5)=O
      Storage:Please store the product under the recommended conditions in the Certificate of Analysis.
      Transportation:Room temperature in continental US; may vary elsewhere.
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    • Description:BDTX-189 is a potent and selective inhibitor of allosteric EGFR and HER2 oncogenic mutations with Kd of 0.2 nM, 0.76 nM, 13 nM and 1.2 nM for EGFR, HER2, BLK and RIPK2, reapectively. BDTX-189 exhibits anticancer activity.
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