BMS 777607
Cat. No. :YN440194
CAS No. :1025720-94-8
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order@ubiochem.com| Product Name: | BMS 777607 |
| CAS NO.: | 1025720-94-8 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 512.89 |
| Molecular Formula: | C₂₅H₁₉ClF₂N₄O₄ |
| SMILES: | O=C(NC1=CC=C(C(F)=C1)OC2=C(C(N)=NC=C2)Cl)C3=C(C=CN(C3=O)C4=CC=C(C=C4)F)OCC |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | BMS-777607 is a Met-related inhibitor for c-Met, Axl, Ron and Tyro3 with IC50 of 3.9 nM, 1.1 nM, 1.8 nM and 4.3 nM in cell-free assays, 40-fold more selective for Met-related targets versus Lck, VEGFR-2, and TrkA/B, and more than 500-fold greater selectivity versus all other receptor and non receptor kinases. Phase 1/2. |
| IC50&Target: | |
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| References: |
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