SAR125844
Cat. No. :YN440362
CAS No. :1116743-46-4
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order@ubiochem.com| Product Name: | SAR125844 |
| CAS NO.: | 1116743-46-4 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 550.63 |
| Molecular Formula: | C₂₅H₂₃FN₈O₂S₂ |
| SMILES: | O=C(NCCN1CCOCC1)NC2=NC3=CC=C(SC4=NN=C5C=CC(C6=CC=C(F)C=C6)=NN54)C=C3S2 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SAR125844 is a potent intravenously active and highly selective MET kinase inhibitor, displaying nanomolar activity against the wild-type kinase (IC50 value of 4.2 nmol/L) and H1094Y, Y1235D, M1250T, L1195V, and D1228H kinase domain mutants (IC50 values of 0.22, 1.7, 6.5, 65, and 81 nmol/L, respectively). |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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