Glumetinib
Cat. No. :YN440170
CAS No. :1642581-63-2
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Product Name: | Glumetinib |
CAS NO.: | 1642581-63-2 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 459.48 |
Molecular Formula: | C₂₁H₁₇N₉O₂S |
SMILES: | O=S(N1N=CC2=NC=C(C3=CN(C)N=C3)C=C21)(C4=CN=C5C=CC(C6=CN(C)N=C6)=CN54)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Glumetinib (SCC244) is a potent and highly selective c-Met inhibitor with an IC50 of 0.42 ± 0.02 nmol/L. Glumetinib has greater than 2,400-fold selectivity for c-Met over those 312 kinases evaluated, including the c-Met family member RON and highly homologous kinases Axl, Mer, and TyrO3. |
IC50&Target: | |
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References: |
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