Ningetinib
Cat. No. :YN440109
CAS No. :1394820-69-9
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Product Name: | Ningetinib |
CAS NO.: | 1394820-69-9 |
Chemical Name: | |
Synonyms: | CT-053, DE-120, CT053PTSA |
Molecular Weight: | 556.58 |
Molecular Formula: | C₃₁H₂₉FN₄O₅ |
SMILES: | CC1=C(C(NC2=CC(F)=C(OC3=CC=NC4=C3C=CC(OCC(C)(O)C)=C4)C=C2)=O)C(N(C5=CC=CC=C5)N1C)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Ningetinib is a potent, orally bioavailable inhibitor of tyrosine kinase with IC50 of 6.7 nM, 1.9 nM and <1.0 nM for c-Met, VEGFR2 and Axl, respectively. Ningetinib exhibits antitumor activity. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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