SYN1143
Cat. No. :YN440376
CAS No. :913376-84-8
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order@ubiochem.com| Product Name: | SYN1143 |
| CAS NO.: | 913376-84-8 |
| Chemical Name: | |
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| Molecular Weight: | 556.58 |
| Molecular Formula: | C₃₁H₂₉FN₄O₅ |
| SMILES: | O=C(C1=C(C)N(CC(C)(O)C)N(C2=CC=CC=C2)C1=O)NC3=CC=C(OC4=CC=NC5=CC(OC)=CC=C45)C(F)=C3 |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | SYN1143 is a potent and selective dual inhibitor ofc-Met/RON, with IC50s of 4 and 9nM, respectively. SYN1143 has weak inhibitory activity onLck,Tie2,Src, and BTKwith IC50s ranging from 160 to 710nM. SYN1143 can be used for the research of cancers that RON and c-Met are activated. |
| IC50&Target: | |
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