Savolitinib
Cat. No. :YN440353
CAS No. :1313725-88-0
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5mg
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Product Name: | Savolitinib |
CAS NO.: | 1313725-88-0 |
Chemical Name: | |
Synonyms: | Volitinib |
Molecular Weight: | 345.36 |
Molecular Formula: | C₁₇H₁₅N₉ |
SMILES: | CN1N=CC(C2=CN=C3C(N([C@H](C4=CN5C(C=C4)=NC=C5)C)N=N3)=N2)=C1 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Savolitinib (volitinib, AZD6094, HMPL-504) is a novel, potent, and selective MET inhibitor currently in clinical development in various indications, including PRCC. The IC50 values of this compound for c-Met and p-Met are 5 nM and 3 nM, respectively. It shows exquisite selectivity for c-Met over 274 kinase. |
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