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Cardiovascular Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN482885 Morusinol 62949-93-3

    Morusinol is a flavonoid isolated fromMorus albaroot bark. Morusinol has anantiplateletactivity and  significantly inhibits arterial thrombosis in vivo.

  • YN320159 Etersalate 62992-61-4

    Etersalate inhibits platelet function and decreasesthromboxane A2(TXA2) levels.

  • YN482719 Hypaconine 63238-68-6

    Hypaconine is a C19-diterpenoid alkaloid isolated fromAconitum and Delphinium spp. Hypaconine exhibits strong cardiac activity.

  • YN330364 Indobufen 63610-08-2

    Indobufen is a reversible platelet aggregation inhibitor. It inhibits the platelet cyclooxygenase enzyme and suppresses thromboxane synthesis.

  • YN321474 Betaxolol 63659-18-7

    Betaxolol is a selective beta1 adrenergic receptor blocker used in the treatment of hypertension and glaucoma.

  • YN321475 Betaxolol hydrochloride 63659-19-8

    Betaxolol is a β1 adrenergic receptor blocker with IC50 of 6 μM.

  • YN330342 Nisoldipine 63675-72-9

    Nisoldipine (Sular) is a calcium channel blocker belonging to the dihydropyridines class, specific for L-type Cav1.2 with IC50 of 10 nM.

  • YN322017 Cicloprolol hydrochloride 63686-79-3

    Cicloprolol is a partialβ 1-adrenoceptoragonist .

  • YN482480 Vitexin-2"-O-rhamnoside 64820-99-1

    Vitexin-2-O-rhamnoside is one of the main components of flavonoid of the leaves of Crataegus pinnatifida Bge. var major N. E. Br. It has many biological and pharmacological activities, such as antioxidation and treating heart diseas...

  • YN321459 Urapidil hydrochloride 64887-14-5

    Urapidil HCl is a hydrochloride salt form of urapidil which is α1-adrenoceptor antagonist and 5-HT1A receptor agonist with pIC50 of 6.13 and 6.4 respectively.

  • YN322081 Bometolol Hydrochloride 65023-16-7

    Bometolol Hydrochloride is abeta-adrenergicblocking agent, used for the research of cardiovascular disease.

  • YN360772 Nicorandil 65141-46-0

    Nicorandil is a potassium channel activator, and stimulates guanylate cyclase to increase formation of cyclic GMP (cGMP).

  • YN484048 Boc-Ile-Glu-Gly-Arg-AMC 65147-06-0

    Boc-Ile-Glu-Gly-Arg-AMC (IEGR-AMC) is an activated factor X (FXa) specific fluorogenic peptide substrate used for Factor VIII determination.

  • YN360756 Nimodipine 66085-59-4

    Nimodipine is a dihydropyridine calcium channel blocker and an autophagy inhibitor, used in the treatment of high blood pressure.

  • YN483729 Z-Gly-Gly-Arg-AMC 66216-78-2

    Z-Gly-Gly-Arg-AMC is a thrombin-specific fluorogenic substrate for testing of thrombin generation in PRP and platelet-poor plasma (PPP).

  • YN360926 Gomisin J 66280-25-9

    Gomisin J is a small molecular weight lignan found inSchis and ra chinensis and has been demonstrated to have vasodilatory activity. Gomisin J suppresses lipid accumulation by regulating the expression of lipogenic and lipolytic enz...

  • YN480471 Ifenprodil glucuronide 66516-92-5

    Ifenprodil glucuronide is a derivative of Ifenprodil. Ifenprodil is a vasodilator and an inhibitor of platelet aggregation, and Ifenprodil glucuronide has no effect on platelet aggregation and arterial contraction.

  • YN310028 BGP-15 66611-37-8

    BGP-15, is a nicotinic amidoxime derivative with PARP inhibitory activity. It has been demonstrated that BGP-15 protects against ischemia-reperfusion injury.

  • YN320666 Bisoprolol 66722-44-9

    Bisoprolol is a cardioselective β1-adrenergic blocking agent used for secondary prevention of myocardial infarction (MI), heart failure, angina pectoris and mild to moderate hypertension.

  • YN360431 Norverapamil 67018-85-3

    Norverapamil ((±)-Norverapamil), an N-demethylated metabolite of Verapamil, is aL-type calcium channelblocker and aP-glycoprotein (P-gp)function inhibitor.

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