YN482422 Yunaconitine 70578-24-4

Yunaconitine(Guayewuanine B) is a highly toxic aconitum alkaloid.

YN481801 Phenindione D5 70711-53-4

Phenindione D5 (Rectadione D5) is deuterium labeled Phenindione, which is an anticoagulant which functions as a Vitamin K antagonist.

YN480014 Prifuroline 70833-07-7

Prifuroline is an antiarrhythmic agent.

YN320250 Bucindolol 71119-11-4

Bucindolol is aβ1-adrenergic receptorblocker, with intrinsic sympathomimetic activity, used in the research of heart failure.

YN440054 AG 1295 71897-07-9

AG 1295 is a selectiveplatelet-derived growth factor receptor (PDGFR)tyrosine-kinase inhibitor. AG1295 abolishes autophosphorylation of the PDGFR whereas not affects the autophosphorylation of the EGF receptor.

YN370763 Leukotriene C4 72025-60-6

Leukotriene C4 is the parent cysteinyl leukotriene produced by the LTC4 synthase catalyzed conjugation of glutathione to LTA4. Leukotriene C4 is produced by neutrophils, macrophages, mast cells, and by transcellular metabolism i...

YN360907 Praeruptorin C 72463-77-5

Praeruptorin C is a main bioactive constituent ofPeucedanum praeruptorum(also known as Bai-Hua Qian Hu). Praeruptorin C is acalciumantagonist with pD2′value of 5.7.

YN360765 Felodipine 72509-76-3

Felodipine is a selective L-type Ca2+ channel blocker with IC50 of 0.15 nM.

YN321872 γ1-MSH 72629-65-3

γ1-MSH is amelanocortin MC3 receptoragonist, with a Ki of 34nM for the rat MC3 receptor. γ1-MSH displays ~40-fold selectivity over MC4 (Ki=1318nM).

YN373974 Rentiapril racemate 72679-47-1

Rentiapril racemate (SA-446 racemate) is the racemate of Rentiapril. Rentiapril is anangiotensin converting enzyme(ACE) inhibitor.

YN361060 Darodipine 72803-02-2

Darodipine (PY 108-068, PY-108068) is a potentcalcium channelantagonist.

YN320212 BW 245C 72814-32-5

BW 245C is aprostanoid DP-receptor (DP1)agonist, used to treat stroke.

YN321368 Carvedilol 72956-09-3

Carvedilol is a non-selective beta blocker/alpha-1 blocker, used to treat congestive heart failure (CHF) and high blood pressure.

YN482027 Iopromide 73334-07-3

Iopromide is a low osmolar, non-ionic X-ray contrast agent for intravascular administration. It functions as a contrast agent by opacifying blood vessels in the path of flow of the contrast agent, permitting radiographic visualization of...

YN350250 Methylnissolin 73340-41-7

Methylnissolin (Astrapterocarpan), isolated fromAstragalus membranaceus, inhibitsplatelet-derived growth factor (PDGF)-BB-induced cell proliferation with an IC50 of 10μM. Methylnissolin inhibits PDGF-BB-induced phosphory...

YN250710 Mevastatin 73573-88-3

Mevastatin is a competitive inhibitor of HMG-Coenzyme A (HMG-CoA) reductase with a binding affinity 10,000 times greater than the HMG-CoA substrate itself.

YN371630 3,4-Dehydro Cilostazol 73963-62-9

3,4-Dehydro Cilostazol (OPC-13015) is an active metabolite of Cilostazol (CLZ; HY-17464). 3,4-Dehydro Cilostazol is used for pharmacokinetic study.

YN372443 Cilostazol 73963-72-1

Cilostazol is a potent cyclic nucleotide phosphodiesterase type 3 (PDE3) inhibitor with IC50 of 0.2 μM and inhibitor of adenosine uptake.

YN372757 Pimobendan 74150-27-9

Pimobendan is a selective inhibitor of PDE3 with IC50 of 0.32 μM.

YN321386 Doxazosin 74191-85-8

Doxazosin is a quinazoline-derivative that selectively antagonizes postsynaptic α1-adrenergic receptors.