YN370426 C16-PAF 74389-68-7

C16-PAF (PAF (C16)), a phospholipid mediator, is a platelet-activating factor and lig and for PAF G-protein-coupled receptor (PAFR). C16-PAF exhibits anti-apoptotic effect and inhibits caspase-dependent death by act...

YN330455 Limaprost 74397-12-9

Limaprost (OP1206) is aPGE1analogue and a potent and orally active vasodilator. Limaprost increases blood flow and inhibits platelet aggregation. Limaprost can be used for pain relief, has antianginal effects, and has potent...

YN321896 Sauvagine 74434-59-6

Sauvagine, a 40-amino-acid neuropeptide from the skin of the frog, is amammalian CRFagonist. Sauvagine is effective at releasing ACTH from rat pituitary cells. Sauvagine possesses a number of pharmacological actions on diuresis, t...

YN320573 Ro 363 74513-77-2

Ro 363 is a potent and highly selectiveβ1-adrenoceptoragonist. RO 363 is an effective inotropic stimulant, and is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractilit...

YN360598 Bepridil hydrochloride hydrat... 74764-40-2

Bepridil hydrochloride is an anti-anginal drug classified as a calcium channel blocker. It also blocks multiple other ion channels, including sodium and potassium channels.

YN372786 Argatroban 74863-84-6

Argatroban is a potent and selective synthetic thrombin inhibitor with Ki ranging from 5 nM to 39 nM, used as an anticoagulant.

YN251600 Kukoamine A 75288-96-9

Kukoamine A is a natural occurring spermine derivative, acts as a potent inhibitor oftrypanothione reductase(Ki, 1.8μM), with antihypertensive activity.

YN373122 Lovastatin 75330-75-5

Lovastatin is an inhibitor of HMG-CoA reductase with IC50 of 3.4 nM in a cell-free assay, used for lowering cholesterol (hypolipidemic agent).

YN320665 Cefminox sodium 75498-96-3

Cefminox Sodium is the sodium salt form of cefminox, a semi-synthetic, second-generation, beta-lactamase-stable cephalosporin with antibacterial activity.

YN360483 Nilvadipine 75530-68-6

Nilvadipine is a potent calcium channel blocker with an IC50 of 0.03 nM.

YN480131 Imanixil 75689-93-9

Imanixil (HOE-402 free base) is an inducer of the LDL receptor (LDLR). Imanixil (HOE-402 free base) is also a potent cholesterol-lowering compound, which inhibits very low density-lipoprotein (VLDL) production, and cons...

YN360751 Isradipine 75695-93-1

Isradipine is a potent and selective L-type voltage-gated calcium channel blocker, used to treat high blood pressure.

YN320008 Ancarolol 75748-50-4

Ancarolol is abeta-adrenergicblocking agent.

YN372777 Enalapril 75847-73-3

Enalapril (MK-421) is an angiotensin converting enzyme (ACE) inhibitor.

YN370769 4-Hydroxynonenal 75899-68-2

4-Hydroxynonenal (4-HNE) is an α,β unsaturated hydroxyalkenal and an oxidative/nitrosative stress biomarker. 4-Hydroxynonenal is a substrate and an inhibitor ofacetaldehyde dehydrogenase 2 (ALDH2). 4-Hydroxynonenal can modu...

YN480823 (R)-Nicardipine 76093-35-1

(R)-Nicardipine ((R)-YC-93 free base) is the less active R enantiomer of Nicardipine. Nicardipine (YC-93) is acalcium channelblocker with an IC50 of 1μM for blocking cardiac calcium channels. Nicardipine acts as an agent for ...

YN480822 (S)-Nicardipine 76093-36-2

(S)-Nicardipine ((S)-YC-93 free base) is the less active S enantiomer of Nicardipine. Nicardipine is acalcium channelblocker with an IC50 of 1μM for blocking cardiac calcium channels. Nicardipine acts as an agent for chronic st...

YN372778 Enalapril maleate 76095-16-4

Enalapril Maleate is an angiotensin-converting enzyme (ACE) inhibitor, used in the treatment of hypertension, diabetic nephropathy, and chronic heart failure.

YN482073 Mildronate 76144-81-5

Mildronate (Meldonium) functions as a cardioprotective drug by cpmpetetively inhibitingBBOX1 and OCTN2. Mildronate (Meldonium) exhibitsIC50 values of 34-62μM for human recombinant BBOX and an EC50 of 21μM for human...

YN360037 Nicainoprol 76252-06-7

Nicainoprol is a fast-sodium-channelblocking drug, which is a potent antiarrhythmic agent.