YN321361 Tasosartan 145733-36-4

Tasosartan is a long-actingangiotensin II(AngII)receptorantagonist.

YN320785 Goserelin acetate 145781-92-6

Goserelin is a luteinizing hormone releasing hormone (LHRH) agonist, which is used to suppress production of the sex hormones.

YN370065 MSDC 0160 146062-49-9

MSDC 0160 (Mitoglitazone) is a mitochondrial target of thiazolidinediones (mTOT)-modulatinginsulin sensitizer and a modulator ofmitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabeti...

YN320220 ZD 7155(hydrochloride) 146709-78-6

ZD 7155 hydrochloride is an angiotensin II receptor type 1 (AT1 receptor) antagonist.

YN321110 Alcaftadine 147084-10-4

Alcaftadine is a high affinity ligand for the H1 receptor, with a pKi (8.5) that is comparable with that of other H1 antihistamines. Alcaftadine is also an antagonist for H2 and H4 receptors with no affinity for the H3 receptor.

YN320054 Maropitant 147116-67-4

Maropitant is a selective and orally activeneurokinin (NK1) receptorantagonist. Maropitant acts by blocking the binding of substance P within the emetic center and the chemoreceptor trigger zone (CRTZ). Maropitant is highly ef...

YN320931 Azilsartan 147403-03-0

Azilsartan is an angiotensin II type 1 (AT1) receptor antagonist with IC50 of 2.6 nM.

YN321323 Bosentan 147536-97-8

Bosentan is a competitive and dual antagonist ofendothelin-1 (ET)for the ETA and ETBreceptors with Kiof 4.7nM and 95nM in human SMC, respectively.

YN322028 MG 1 148274-76-4

MG 1 is an α1adrenergic receptorantagonist.

YN321806 Substance P TFA 148470-19-3

Substance P TFA (Neurokinin P TFA) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P isneurokinin 1 receptor(NK1-receptor,NK1R).

YN321399 Ivabradine hydrochloride 148849-67-6

Ivabradine HCl, a new If inhibitor with IC 50 of 2.9 μM which acts specifically on the pacemaker activity of the sinoatrial node, is a pure heart rate lowering agent.

YN320178 QF0301B 149247-12-1

QF0301B is anα1 adrenergic receptorantagonist and a low α2 adrenoceptor, 5-HT2A, and histamine H1 receptor blocker.

YN373976 CGP-53153 149281-19-6

CGP-53153 is a steroidal inhibitor of5 alpha reductasewith IC50s of 36 and 262nM in rat and human prostatic tissue, respectively.

YN321210 Elisartan 149968-26-3

Elisartan is an orally active non-peptide pro-drug ofangiotensin II AT1 receptorantagonist HN-12206, and shows anti-hypertension activities.

YN321207 Terbogrel 149979-74-8

Terbogrel is an orally availablethromboxane A2 receptorantagonist and athromboxane A2 synthaseinhibitor, with bothIC50s of about 10nM.

YN321100 Tolvaptan 150683-30-0

Tolvaptan is an orally effective nonpeptide arginine vasopressin V2 receptor antagonist with IC50 of 3 nM, used to treat hyponatremia.

YN321228 Ro 46-2005 150725-87-4

Ro 46-2005 is a novel synthetic non-peptide endothelin receptor antagonist, inhibits the specific binding of 125I-ET-1 to human vascular smooth muscle cells (ETA receptor) with IC50 of 220nM.

YN484010 Phosphorylase Kinase β-Sub... 150829-21-3

Phosphorylase Kinase β-Subunit Fragment (420-436) is the β-Subunit fragment (peptide 430-436) of phosphorylase kinase. Phosphorylase kinase is a serine/threonine-specific protein kinase which activates glycogen phosphorylase to rele...

YN321427 Nebivolol hydrochloride 152520-56-4

Nebivolol HCl selectively inhibits β1-adrenoceptor with IC50 of 0.8 nM.

YN321579 Fexofenadine hydrochloride 153439-40-8

Fexofenadine inhibits histamine H1 receptor with IC50 of 246 nM.