YN320152 Pratosartan 153804-05-8

Pratosartan is a selectiveangiotensin II receptorantagonist.

YN322052 L162441 154512-46-6

L162441 is anAngiotensin type 1 receptorantagonist.

YN480279 RU 58841 154992-24-2

RU58841, also known as PSK-3841 or HMR-3841, is a non-steroidal anti-androgen.

YN321289 Plerixafor octahydrochloride 155148-31-5

Plerixafor 8HCl (AMD3100 8HCl) is the hydrochloride of Plerixafor, a chemokine receptor antagonist for CXCR4 and CXCL12-mediated chemotaxis with IC50 of 44 nM and 5.7 nM in cell-free assays, respectively.

YN321412 Bimatoprost 155206-00-1

Bimatoprost is a prostaglandin analog used topically (as eye drops) to control the progression of glaucoma and in the management of ocular hypertension.

YN320919 Sograzepide 155488-25-8

Sograzepide (Netazepide; YF 476; YM-220) is an extremely potent , highly selective  and orally activeGastrin/CCK-Bantagonist with an IC50 value of 0.1nM, has inhibitory effect on Gastrin/CCK-A activity with an IC5...

YN483845 Lys-γ3-MSH(human) 156159-18-1

Lys-γ3-MSH(human) is a melanocortin peptide derived from the C-terminal of the fragment of pro-opiomelanocortin (POMC). Lys-γ3-MSH(human) potentiates the steroidogenic response of the rat adrenal to adrenocorticotrophin (AC...

YN321046 BQ-788 sodium salt 156161-89-6

BQ-788 sodium salt is a potent and selectiveETB receptorantagonist, inhibiting ET-1 binding to ETB receptors with an IC50 of 1.2nM in human Girrardi heart cells.

YN470006 ZK159222 156965-15-0

ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent1α,25-(OH)2D3 receptor (VDR)antagonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of lig and -induced vitamin D receptor inte...

YN321324 Bosentan (hydrate) 157212-55-0

Bosentan is an endothelin (ET) receptor antagonist for ET-A and ET-B with Ki of 4.7 nM and 95 nM, respectively.

YN321208 L-159282 157263-00-8

L-159282 is a highly potent, orally active, nonpeptideangiotensin II receptorantagonist, with anti-hypertensive activity.

YN321543 Travoprost 157283-68-6

Travoprost is a PGF2a analog that was launched as an ophthalmic solution administered topically for the treatment of elevated intraocular hypertension as a result of open-angle glaucoma, a common optic neuropathy, and a leading cause of...

YN320334 GR 159897 158848-32-9

GR 159897 is a highly potent, selective, competitive, brain-penetrated non-peptideneurokinin 2 (NK2) receptorantagonist. GR 159897 has little or no affinity for NK1 and NK3receptors. GR 159897 inhibits binding of [3H]GR10067...

YN350186 FR 167653 free base 158876-65-4

FR 167653 free base, an orally active and selectivep38 MAPKinhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 free base is effective in treating inf...

YN350187 FR 167653 158876-66-5

FR 167653 (FR 167653 sulfate), an orally active and selectivep38 MAPKinhibitor, is a potent suppressor of TNF-α and IL-1β production via specific inhibition of p38 MAPK activity. FR 167653 (FR 167653 sulfate) is e...

YN321215 L755507 159182-43-1

L-755,507 is characterized as a potent and selective β3 adrenergic receptor partial agonist with EC50 of 0.43 nM. It is also recently identified to enhance CRISPR-mediated homology-directed repair (HDR) efficiency in human in...

YN321812 A 779 159432-28-7

A 779 is a specific antagonist of G-protein coupled receptor (Mas receptor), which is anAng1-7 receptordistinct from the classical AngII.

YN322041 LY285434 159748-08-0

LY285434 is a suitableangiotensin II receptorantagonist.

YN321286 Ibutamoren Mesylate 159752-10-0

Ibutamoren Mesylate (MK-677) is a potent, non-peptide Growth hormone secretagogue receptor (GHSR)agonist. Ibutamoren Mesylate is an orally active growth hormone (GH) secretagogue.

YN481416 Ulipristal 159811-51-5

Ulipristal is a selective SPRM for emergency contraception after an unprotected intercourse or contraceptive failure.