YN320378 L-368,899 hydrochloride 160312-62-9

L-368,899 hydrochloride is a potent, selective, orally bioavailable, non-peptideoxytocin receptorantagonist, with IC50s of 8.9nM and 26nM for rat uterus and human uterus oxytocin receptor, respectively, used as a tocolytic agent.

YN320113 Silodosin 160970-54-7

Silodosin is a highly selective α1A-adrenoceptor antagonist, used in treatment of benign prostatic hyperplasia.

YN320441 Desisobutyryl-ciclesonide 161115-59-9

Desisobutyryl-ciclesonide is the active metabolite of Ciclesonide. Desisobutyryl-ciclesonide has affinity for theglucocorticoid receptor.

YN360608 Esomeprazole sodium 161796-78-7

Esomeprazole Sodium is a sodium salt of esomeprazole that is a potent proton pump inhibitor with an IC50 of 0.076 mg/kg.

YN360606 Esomeprazole potassium salt 161796-84-5

Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of theH+, K+-ATPasein gastric parietal cells. Esomeprazole potassium ...

YN322066 α1 adrenoceptor-MO-1 161905-64-2

α1 adrenoceptor-MO-1, an S enantiomer, has affinity atalpha 1 adrenergic receptor, shows alphalytic activity, and possesses analgesic action; more active than R enantiomer.

YN360867 Esomeprazole magnesium 161973-10-0

Esomeprazole Magnesium is a proton pump inhibitor to reduce gastric acid secretion.

YN320940 L-371,257 162042-44-6

L-371,257 is an orally bioavailable, non-blood-brain barrier penetrant, selective and competitive antagonist ofoxytocin receptor(pA2=8.4) with high affinity at both the oxytocin receptor (Ki=19nM) and vasopressin V1a receptor(Ki=3....

YN322079 Gastrin/CCK antagonist 1 162271-52-5

Gastrin/CCK antagonist 1 is an antagonist ofgastrin/CCK, used for the research of gastrointestinal disorders.

YN484261 Carbazole derivative 1 164914-28-7

Carbazole derivative 1 is a carbazole derivative which can be used to reduce and rogen or oestrogen levels in mammals, including humans.

YN321098 Terutroban 165538-40-9

Terutroban is athromboxane-prostagl and in receptorantagonist.

YN320161 OPC-28326 167626-17-7

OPC-28326 is a selective peripheral vasodilator and an angatonist ofα2-adrenergic receptor, with Kiof 2040, 285, and 55 nM for α2A-, α2B- and α2C-adrenoceptors, respectively.

YN322072 CHEMBL333994 167820-10-2

CHEMBL333994 is a potent and orally effective Cholecystokinin A(CCK-A)antagonist, with an IC50 of 0.67nM.

YN320833 Lixivaptan 168079-32-1

Lixivaptan (VPA-985, WAY-VPA 985) is an orally active and selectivevasopressin receptorV2 antagonist, with IC50 values of 1.2 and 2.3nM for human and rat V2, respectively.

YN320551 Vofopitant dihydrochloride 168266-51-1

Vofopitant dihydrochloride (GR 205171A) is a potent, selective and orally available tachykinin neurokinin 1(NK1) receptor antagonist, inhibits [3H]SP binding to the NK1 receptor with pKi values. of 9.5 and 10.6 in rat and ...

YN320550 Vofopitant 168266-90-8

Vofopitant is potenttachykinin NK1receptorantagonist, withpKis of 10.6, 9.5, and 9.8 for human, rat and ferret NK1receptor, respectively.

YN321184 Conivaptan hydrochloride 168626-94-6

Conivaptan HCl is an orally active, non-peptide, vasopressin V1A and V2 receptor antagonist, used in the treatment of euvolemic and hypervolemic hyponatremia.

YN320133 RS 17053 hydrochloride 169505-93-5

RS 17053 hydrochloride is a potent and selectiveα1Aadrenoceptorantagonist, with apKivalue of 9.1 in native cell membrane and apA2value of 9.8 in functional assays.

YN320190 ReN-1869 hydrochloride 170149-76-5

ReN 1869 hydrochloride is a novel, selectivehistamine H1receptorantagonist, which demonstrates affinity to the histamine H1receptor (guinea pig brain) with Kiof 0.19±0.04μM and the non-selective σ site (guinea pig brain) with Ki...

YN320031 KW-8232 free base 170365-25-0

KW-8232 free base is an anti-osteoporotic agent, and can reduces the biosynthesis of PGE2.