Tanespimycin
Cat. No. :YN370232
CAS No. :75747-14-7
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5mg
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Product Name: | Tanespimycin |
CAS NO.: | 75747-14-7 |
Chemical Name: | |
Synonyms: | CP127374,NSC-330507, KOS 953 |
Molecular Weight: | 585.69 |
Molecular Formula: | C₃₁H₄₃N₃O₈ |
SMILES: | O=C(C(NC(/C(C)=C/C=C[C@H](OC)[C@H](/C(C)=C/[C@@H]([C@H]([C@H](C[C@@H](C1)C)OC)O)C)OC(N)=O)=O)=CC2=O)C1=C2NCC=C |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Tanespimycin (17-AAG) is a potent HSP90 inhibitor with IC50 of 5 nM in a cell-free assay, having a 100-fold higher binding affinity for HSP90 derived from tumour cells than HSP90 from normal cells. Phase 2. |
IC50&Target: | |
In Vitro: | |
In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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