YN290537 Caulophyllogenin 52936-64-8

Caulophyllogenin is a triterpene saponin extracted fromM. polimorpha. Caulophyllogenin is a partialPPARγagonist, with an EC50 of 12.6 μM. Caulophyllogenin can be used for the research of type-2 diabetes, obesity, metabolic sy...

YN370152 Cyclo(his-pro) 53109-32-3

Cyclo(his-pro) (Cyclo(histidyl-proline)) is an orally active cyclic dipeptide structurally related to tyreotropin-releasing hormone. Cyclo(his-pro) could inhibitNF-κBnuclear accumulation. Cyclo(his-pro) can cross the brain-blood-bar...

YN330435 Acemetacin 53164-05-9

Acemetacin is a non-steroidal anti-inflammatory drug and a glycolic acid ester of indometacin that is a cyclooxygenase inhibitor.

YN321557 Pirfenidone 53179-13-8

Pirfenidone is an inhibitor for TGF-β production and TGF-β stimulated collagen production, reduces production of TNF-α and IL-1β, and also has anti-fibrotic and anti-inflammatory properties. Phase 3.

YN482479 2"-O-Galloylhyperin 53209-27-1

2"-O-Galloylhyperin, an active compound isolated fromPyrola incarnateFisch., possesses anti-oxidative and anti-inflammatory activities. 2"-O-Galloylhyperin has hepatoprotective effect against oxidative stress-induced liver damage.

YN483092 Luteolin-3-O-beta-D-glucuro... 53527-42-7

Luteolin-3-O-beta-D-glucuronide is a luteolin glucosiduronic acid consisting of luteolin having a beta-D-glucosiduronic acid residue attached at the 3'-position.

YN350119 Muramyl dipeptide 53678-77-6

Muramyl dipeptide (MDP) is a syntheticimmunoreactive peptide, consisting of N-acetyl muramic acid attached to a short amino acid chain of L-Ala-D-isoGln. Muramyl dipeptide is an inducer ofbone formationthrough induction ofRunx2. ...

YN330089 Armillarisin A 53696-74-5

Armillarisin A has the potential for the ulcerative colitis (UC) study. Armillarisin A increases IL-4 and lower IL-1β.

YN330472 Carprofen 53716-49-7

Carprofen inhibits canine COX2 with IC50 of 30 nM.

YN330173 L-NIL 53774-63-3

L-NIL is aninducible NO synthaseinhibitor, with an IC50 of 3.3μM for miNOS .

YN320842 Lodoxamide 53882-12-5

Lodoxamide (U-42585E free acid) is an antiallergic compound acting as a mast-cell stabilizer for the treatment of asthma and allergic conjunctivitis.

YN321419 Tranilast 53902-12-8

Tranilast?is an antiallergic drug by inhibiting lipid mediator and cytokine release from inflammatory cells, used for the treatment of allergic disorders such as asthma, allergic rhinitis and atopic dermatitis.

YN482827 Hederagenin 28-O-beta-D-glu... 53931-25-2

Hederagenin 28-O-beta-D-glucopyranosyl ester, a triterpenoid saponin isolated fromIlex cornuta, exhibits protective effects against H2O2-induced myocardial cell injury.

YN330269 1-Hydroxy-ibuprofen 53949-53-4

1-Hydroxy Ibuprofen is ametaboliteof Ibuprofen inP. australis. Ibuprofen is an anti-inflammatory inhibitor targetingCOX-1 and COX-2with IC50s of 13μM and 370μM, respectively.

YN481732 Monoammonium glycyrrhizinate ... 53956-04-0

Glycyrrhizic acid ammonium salt has wound healing activity.

YN251113 Sucralfate 54182-58-0

Sucralfate (Sucrose octasulfate-aluminum complex) is a potent and orally activegastroprotectantwith no systemic effects. Sucralfate inhibits peptic activity and binds to negatively charged subepithelial proteins exposed during mucosa...

YN320772 Cimetidine sulfoxide 54237-72-8

Cimetidine sulfoxide (Cimetidine sulphoxide) is a sulfoxide metabolite of Cimetidine. Cimetidine is ahistamine H2-receptorantagonist. Cimetidine has the potential for peptic ulcer disease and upper gastrointestinal haemorrhage treat...

YN480982 6-Hydroxyluteolin 7-glucoside 54300-65-1

6-Hydroxyluteolin 7-glucoside is a flavonoid fromTanacetum parthenium and T. vulgare. 6-Hydroxyluteolin 7-glucoside inhibits the major pathways of arachidonate metabolism in leukocytes. 6-Hydroxyluteolin 7-glucoside has anti-inflammato...

YN250335 c-di-AMP 54447-84-6

c-di-AMP (Cyclic diadenylate) is aSTINGagonist, which binds to the transmembrane protein STING thereby activating the TBK3-IRF3 signaling pathway, subsequently triggering the production of type I IFN and TNF. c-...

YN482658 Oxysophoridine 54809-74-4

Oxysophoridine (Sophoridine N-oxide) is a bioactive alkaloid extracted from theSophora alopecuroidesLinn. Oxysophoridine (Sophoridine N-oxide) shows anti inflammatory, anti oxidative stress and antiapoptosiseffects.