YN320519 Iferanserin 58754-46-4

Iferanserin (S-MPEC) is a selective5-HT receptor(serotonin receptor) antagonist with an affinity for5-HT2Areceptor. Iferanserin has the potential for internal hemorrhoid disease treatment.

YN482407 Toosendanin 58812-37-6

Toosendanin, a triterpenoid extracted from the bark of fruit of Melia toosendan Sieb et Zucc, possesses analgesic, insecticidal and anti-inflammatory activities.

YN320475 H-Val-Pro-Pro-OH 58872-39-2

H-Val-Pro-Pro-OH, a milk-derived proline peptides derivative, is an inhibitor of Angiotensin I converting enzyme(ACE), with an IC50 of 9μM.

YN250077 Sinefungin 58944-73-3

Sinefungin is a potent inhibitor of virion mRNA(guanine-7-)-methyltransferase, mRNA(nucleoside-2'-)-methyltransferase, and viral multiplication. Sinefungin, aSET7/9inhibitor, ameliorates renal fibrosis by inhibiting H3K4 meth...

YN310240 Ingenol 3,20-dibenzoate 59086-90-7

Ingenol 3,20-dibenzoate is a potentprotein kinase C (PKC)isoform-selective agonist. Ingenol 3,20-dibenzoate induces selective translocation of nPKC-delta, -epsilon, and -theta and PKC-mu from the cytosolic fraction to the pa...

YN482018 Cephalosporin C zinc salt 59143-60-1

Cephalosporin C zinc salt is a potent inhibitor ofSAMHD1with an IC50 of 1.1μM.

YN484182 Diflucortolone valerate 59198-70-8

Diflucortolone valerate is a potent corticosteroid esterified with valeric acid. It helps reduce swelling, itching, and redness.

YN483276 Darutoside 59219-65-7

Darutoside is a diterpenoid isolated from Siegesbeckia.

YN371562 Camostat mesylate 59721-29-8

Camostat is a trypsin-like protease inhibitor, inhibits airway epithelial sodium channel (ENaC) function with IC50 of 50 nM, less potent to trpsin, prostasin and matriptase.

YN330433 Tenoxicam 59804-37-4

Tenoxicam is a good HO. radicals scavenger with an IC50 of 56.7 μM.

YN330445 Cyclosporin A 59865-13-3

Cyclosporin A is an immunosuppressive agent, binds to the cyclophilin and then inhibits calcineurin with IC50 of 7 nM in a cell-free assay, widely used in organ transplantation to prevent rejection.

YN251481 Glabridin 59870-68-7

Glabridin, one of the active phytochemicals in licorice extract, binds to and activates the ligand binding domain of PPARγ, as well as the full length receptor. It is also a GABAA receptor positive modulator promoting fatty acid...

YN270599 N-Formyl-Met-Leu-Phe 59880-97-6

N-Formyl-Met-Leu-Phe (fMLP; N-Formyl-MLF) is a chemotactic peptide and a specific lig and of N-formyl peptide receptor (FPR). N-Formyl-Met-Leu-Ph is reported to inhibitTNF-alphasecretion.

YN482536 Cucurbitacin S 60137-06-6

Cucurbitacin S is isolated fromcucurbitaceaewith anticancer and anti-inflammatory activities.

YN321219 Sulprostone 60325-46-4

Sulprostone (SHB 286) is a potent and selectiveEP3 receptoragonist. Sulprostone (SHB 286) is a prostagl and in E2 (PGE2) analogue and has antiulcer and nonsteroidal abortifacient effects. Sulprostone has potential for t...

YN360118 DCEBIO 60563-36-2

DCEBIO, a derivative of 1-EBIO, is an extremely potent activator ofCl－secretionin T84 colonic cells. DCEBIO stimulates Cl－secretion via the activation of hIK1 K＋channels and the activation of an apical membrane C...

YN320572 Oxatomide 60607-34-3

Oxatomide is a potent and orally active dualH1-histamine receptor and P2X7 receptorantagonist with antihistamine and anti-allergic activity. Oxatomide almost completely blocks the ATP-induced current inhuman P2X7 receptors(IC...

YN360466 Ebselen 60940-34-3

Ebselen is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.

YN270465 Geraniin 60976-49-0

Geraniin, a hydrolysable polyphenol derived from Nephelium lappaceum L. fruit rind, has been shown to possess significant antioxidant activity in vitro.The IC50 values of TNF-α release inhibition were 43 μM for ger...

YN484184 Tiopinac 61220-69-7

Tiopinac (RS 40974), a dibenzthiepin, is an orally active and highly potent anti-inflammatory, analgesic and anti-pyretic agent.