YN321698 Betahistine mesylate 54856-23-4

Betahistine mesylate is the mesylate salt form of Betahistine, a histamine analog and H3 receptor agonist that serves as a vasodilator.

YN330353 Dapansutrile 54863-37-5

Dapansutrile (OLT1177) is a novel and selective NLRP3 inflammasome inhibitor.

YN410147 Ergolide 54999-07-4

Ergolide is a sesquiterpene lactone isolated from the dried flowers ofInula Britannica. Ergolide inhibits inducible nitric oxide synthase and cyclo-oxygenase-2 expression in RAW 264.7 macrophages through the inactivation ofNF-κB...

YN372729 Acitretin 55079-83-9

Acitretin is a second generation retinoid used for psoriasis.

YN251675 Skullcapflavone II 55084-08-7

Skullcapflavone II, a flavonoid derived fromScutellaria baicalensis, has anti-inflammatory, anti-microbial activities. Skullcapflavone II regulates osteoclast differentiation, survival, and function. Skullcapflavone II exerts po...

YN320022 Pirolate 55149-05-8

Pirolate is ahistamine H1receptor.

YN410035 MnTBAP chloride 55266-18-7

MnTBAP chloride is a superoxide dismutase (SOD) mimetic and peroxynitrite scavenger. MnTBAP chloride is a manganic porphyrin complex and has anti-oxidative property. MnTBAP chloride mediates anti-inflammatory effects t...

YN330184 Soyasaponin II 55319-36-3

Soyasaponin II is a saponin with antiviral activity. Soyasaponin II inhibits the replication of HSV-1, HCMV, influenza virus, and HIV-1. Soyasaponin II shows potent inhibition on HSV-1 replication. Soyasaponin II ...

YN1710032 Hibifolin 55366-56-8

Hibifolin, a flavonol glycoside, is a potential inhibitor ofadenosine deaminase (ADA), with aKiof 49.92μM. Hibifolin protects neurons against beta-amyloid-induced neurotoxicity.

YN370473 Furamidine dihydrochloride 55368-40-6

Furamidine dihydrochloride (DB75 dihydrochloride) is a selectiveprotein arginine methyltransferase 1 (PRMT1)inhibitor with an IC50 of 9.4μM. Furamidine dihydrochloride is selective forPRMT1over PRMT5, PRMT6, and P...

YN482592 IKarisoside A 55395-07-8

IKarisoside A(Icarisoside-A) is a natural compound isolated from Epimedium koreanum (Berberidaceae); has anti-inflammatory properties.

YN321724 Anisodamine hydrobromide 55449-49-5

Anisodamine is a naturally occurring atropine derivative and exhibits anti-inflammatory activity. It also inhibits α1-adrenergic receptors and muscarinic acetylcholine receptors (mAChRs).

YN481590 Guacetisal 55482-89-8

Guacetisal is obtained from the esterification of acetylsalicylic acid with guaiacol which has the potential for chronic bronchitis treatment extracted from patent CN 106866420 A.

YN372607 Secalciferol 55721-11-4

Secalciferol is a metabolite of Vitamin D, a possibly anti-inflammatory steroid which is involved in bone ossification. In addition, it is known that Secalciferol mediates calcium and phosphorus homeostasis. Also Secalciferol inhi...

YN330573 Crocin II 55750-84-0

Crocin II is isolated from the fruit ofGardenia jasminoideswith antioxidant, anticancer, and antidepressant activity. Crocin II inhibits NO production with an IC50 value of 31.1μM. Crocin II suppresses the expressions of p...

YN483329 Crocin III 55750-85-1

Crocin III is a crocetin from saffron (Crocus sutivusL.). Crocetins inhibit cell growth of tumor cells and has anti-inflammatory activity. Crocins serve as spices and coloring agents .

YN450144 Halofuginone 55837-20-2

Halofuginone is the competitively inhibitor of prolyl-tRNA synthetase with Ki of 18.3 nM.It could also down-regulate Smad3 and blocked TGF-β signaling at 10 ng/ml in mammal.

YN350243 4-Hydroxylonchocarpin 56083-03-5

4-Hydroxylonchocarpin is a chalcone compound from an extract ofPsoralea corylifolia. 4-Hydroxylonchocarpin increases phosphorylation of p38 MAPK, JNK and ERK. 4-Hydroxylonchocarpin has diverse pharmacological activities, inc...

YN373306 Aurantiamide acetate 56121-42-7

Aurantiamide acetate (TMC-58A) is a selective and orally activecathepsininhibitor isolated fromPortulaca oleracea L. Aurantiamide acetate has anti-inflammatory activities and can be used for the study of  inflammatory diseases...

YN310244 Valrubicin 56124-62-0

Valrubicin is a chemotherapy agent, inhibits TPA- and PDBu-inducedPKCactivation with IC50s of 0.85 and 1.25μM, respectively, and has antitumor and antiinflammatory activity.