YN484421 Cyclosporin D 63775-96-2

Cyclosporin D, a metabolite of Cyclosporin A, is a weak immunosuppressant. Cyclosporin D is used as internal st and ard for quantification of Cyclosporin A. Cyclosporin A is a potent immunosuppressant drug, suppress T cell activa...

YN330464 Zomepirac sodium salt 64092-48-4

Zomepirac sodium salt (McN-2783-21-98) is a potentprostagl and in biosynthesisinhibitor. Zomepirac sodium salt is a non-steroidal anti-inflammatory drug (NSAID). Zomepirac sodium salt can cause immune-mediated liver injury.

YN372312 4'-Hydroxy diclofenac 64118-84-9

4'-Hydroxy diclofenac is an orally active metabolite of Diclofenac (HY-15036) by cytochrome P450 2C9 (CYP2C9). 4'-Hydroxy diclofenac has anti-inflammatory and analgesic properties.

YN482443 Picroside III 64461-95-6

Picroside III is an iridoid glycoside isolated fromPicrorhiza scrophulariiflora(PS), a traditional Chinese medicine.

YN330485 Tolmetin sodium dihydrate 64490-92-2

Tolmetin is a non-steroidal anti-inflammatory drug of the arylalkanoic acids.

YN251411 Sofalcone 64506-49-6

Sofalcone, a gastric antiulcer agent in clinical use, is known to induce the expression of Heme oxygenase-1 (HO-1) in gastric epithelium.

YN480126 Ibuprofen piconol 64622-45-3

Ibuprofen is a nonsteroidal anti-inflammatory agent (NSAIA) or nonsteroidal anti-inflammatory drug (NSAID), with analgesic and antipyretic properties.

YN330643 Isoforskolin 64657-21-2

Isoforskolin is the principle active component ofC. forskohliinative to China. Isoforskolin reduces the secretion of lipopolysaccharide (LPS)-induced cytokines, namelyTNF-α,IL-1β,IL-6 and IL-8, in human mononuclear leukocy...

YN320469 7α,25-Dihydroxycholesterol 64907-22-8

7α, 25-dihydroxycholesterol (7α,25-OHC) is a potent and selective agonist and endogenous lig and of the orphan GPCR receptorEBI2 (GPR183). 7α, 25-dihydroxycholesterol is highly potent at activating EBI2 (EC50=140 p...

YN482581 Schisantherin E 64917-83-5

Schisantherin E is a natural compound isolated from the active fraction of the fruits of Schis and ra sphenanthera Rehd. et Wils.

YN450145 Halofuginone hydrobromide 64924-67-0

Halofuginone hydrobromide (RU-19110 hydrobromide) is a less-toxic form of Febrifugine, which is isolated from the plantDichroa febrifuga. Halofuginone inhibitsprolyl-tRNA synthetasein an ATP-dependent manner with a Ki of 18.3nM...

YN330238 Ibuprofen Impurity F 65322-85-2

Ibuprofen Impurity F is an Ibuprofen impurity. Ibuprofen is an anti-inflammatory inhibitor targetingCOX-1 and COX-2with IC50s of 13μM and 370μM, respectively.

YN330570 Esculentoside A 65497-07-6

Esculentoside A, isolated from the Chinese herb phytolacca esculenta, possesses a broad inhibitory effect on a panel of pro-inflammation molecules with less toxicity.

YN481982 Glafenine hydrochloride 65513-72-6

Glafenine is an anthranilic acid derivative with analgesic properties, which has been used previously in the treatment of pain.

YN482372 (E/Z)-Polydatin 65914-17-2

Polydatin is a crystal component extracted from the root stem of perennial herbage Polygonum Cuspidatum Sieb.et Zucc.

YN251509 Punicalin 65995-64-4

Punicalin is a hydrolyzable tannin isolated fromPunica granatumL. or the leaves ofTerminalia catappaL.. Punicalin is a anti-hepatitis B virus (HBV)agent and has anti-inflammatory activity.

YN482857 Gomisin H 66056-20-0

Gomisin H is a dibenzocyclooctadiene lignan isolated from the fruits ofSchiz and ra chinensisBAILL.

YN483549 Cimicifugoside 66176-93-0

Cimicifugoside is a triterpenoid originating from the rhizomes of Cimicifuga simplex, and acts to inhibit the subcellular transport of nucleosides.

YN320308 Furprofen 66318-17-0

Furprofen is an non-steroidal anti-inflammatory drug (NSAID) with analgesic properties. Furprofen acts via the inhibition ofprostagl and in (PGE) synthesis. Furprofen can be treated orally for the relief of pain .

YN410071 Dimethyl fumarate D6 66487-95-4

Dimethyl fumarate D6 is a deuterium labeled Dimethyl fumarate. Dimethyl fumarate is a nuclear factor (erythroid-derived)-like 2 (Nrf2) pathway activator and induces upregulation of antioxidant gene expression .