YN321260 MK-571 sodium salt 115103-85-0

MK-571 sodium salt is a selective, orally activeleukotriene D4 receptorantagonist, with Kis of 0.22 and 2.1nM in guinea pig and human lung membranes.

YN482293 TMRM 115532-49-5

TMRM is a cell-permeant cationic lipophilic red fluorescent dye (λex=530nM, λem=592nM).

YN361058 SKF96067 115607-61-9

SKF96067 is a reversible inhibitor of the gastricH+/K+-ATPase.

YN484178 PAF-AN-1 115621-84-6

PAF-AN-1 is a platelet activating factor receptor (PAF) antagonist.

YN290159 CI 972 anhydrous 115787-68-3

CI 972 anhydrous is a potent, orally active, and competitive inhibitor ofpurine nucleoside phosphorylase (PNP)(Ki=0.83μM) under development as a T cell-selective immunosuppressive agent.

YN482948 Tubeimoside III 115810-13-4

Tubeimoside III, a triterpenoid saponin isolated from a Chinese folk medicine"Tubeimu", shows anti-inflammatory, anti-tumor, anti-tumorigenic activities, and acute toxicity in vivo.

YN483583 N-Hydroxypipecolic acid 115819-92-6

N-Hydroxypipecolic acid (1-Hydroxy-2-piperidinecarboxylic acid), a plant metabolite and a systemic acquired resistance (SAR) regulator, orchestrates SAR establishment in concert with the immune signal salicylic acid. N-Hydroxyp...

YN373500 Histatin 5 115966-68-2

Histatin 5 inhibits the activity of the host matrix metalloproteinasesMMP-2 and MMP-9with IC50s of 0.57 and 0.25μM, respectively.

YN482676 Complanatuside 116183-66-5

Complanatuside is a flavonoid found in the traditional Chinese medicine Semen Astragali Complanati.

YN482840 6-Formyl-isoophiopogonanone A 116291-82-8

6-Formyl-isoophiopogonanone A is a homoisoflavonoidal extracted fromOphiopogon japonicas, with antioxidant activity.

YN370342 Nitecapone 116313-94-1

Nitecapone (OR-462) is an orally active and short-actingcatechol-O-methyltransferase (COMT)inhibitor with gastroprotective and antioxidant properties. Nitecapone (OR-462) scavenges reactive oxygen and nitric radicals and ...

YN482969 Loureirin C 116384-24-8

Loureirin C, isolated from "Dragon’s blood", which is a deep red resin obtained from a variety of plant sources. The resin extracted from stems ofDracaena cochinchinensisis one such source of “dragon’s blood”, has a reputation for ...

YN321570 Ramatroban 116649-85-5

Ramatroban (BAY u 3405) is a thromboxane A2(TxA2) receptor antagonist with Ki value of 10 to 13 nM. It also antagonizes a newly identified PGD2 receptor, CRTh2 expressed on the inflammatory cells.

YN330284 FK 3311 116686-15-8

FK-3311 is a selective, cell-permeable and orally available inhibitor of cyclooxygenase-2 (COX-2) with antiinflammatory. FK-3311 has protective effects against hepatic warm ischemia-reperfusion injury by marked inhibition of <...

YN483772 Fmoc-Thr[GalNAc(Ac)3-α-... 116783-35-8

AZP-531 is an analogue of unacylated ghrelin designed to improve glycaemic control and reduce weight.

YN483382 Usaramine N-oxide 117020-54-9

Usaramine N-oxide, a flavonoid isolated fromCrotalaria pallida, possesses anti-inflammatory activities.

YN482742 3'-Hydroxypuerarin 117060-54-5

3'-Hydroxypuerarin is an isoflavone isolated from the roots ofPueraria lobata(Willd.) Ohwi. 3'-Hydroxypuerarin is a antioxidant, which shows marked ONOO(-), NO•, total ROS scavenging activities .

YN410028 FW1256 117089-08-4

FW1256 is a phenyl analogue and a slow-releasing hydrogen sulfide (H2S) donor. FW1256 inhibitsNF-κBactivity and induces cellapoptosis. FW1256 exerts potent anti-inflammatory effects and has the potential for cancer and c...

YN321807 Endothelin 1 (swine, human) 117399-94-7

Endothelin 1 (swine, human) is a synthetic peptide with the sequence of human and swine Endothelin 1, which is a potent endogenous vasoconstrictor. Endothelin 1 acts through two types of receptors ETA and ETB.

YN320460 LY223982 117423-74-2

LY223982 is a potent and specific inhibitor ofleukotriene B4 receptor, with an IC50 of 13.2nM against [3H]LTB4 binding to LTB4 receptor.