YN330277 NS-398 123653-11-2

NS-398 is a selective inhibitor of cyclooxygenase-2 (COX-2). The IC50 values for human recombinant COX-1 and -2 are 75 and 1.77 μM, respectively.

YN330337 Iguratimod 123663-49-0

Iguratimod is a small molecule compound with anti-inflammatory and immunomodulatory actions and used for the treatment of rheumatoid arthritis.

YN373565 Acetyl-Calpastatin(184-210)(... 123714-50-1

Acetyl-Calpastatin(184-210)(human) is a potent, selective and reversiblecalpaininhibitor with Ki values of 0.2nM and 6μM for µ-calpain and cathepsin L, respectively.

YN1710029 GR79236 124555-18-6

GR79236 is a highly potent, selective and orally activeadenosine A1 receptoragonist with aKis of 3.1nM and 1300nM forA1 and A2 receptors, respectively. GR79236 has anti-nociceptive and anti-inflammatory actions.

YN483080 6"-O-Malonyldaidzin 124590-31-4

6"-O-Malonyldaidzin is a malonylated isoflavone isolated from soybean seeds. 6"-O-Malonyldaidzin may has protective effect on eye.

YN330111 CU-CPT-8m 125079-83-6

CU-CPT-8m is a specificTLR8antagonist, with an IC50 of 67nM.

YN251310 Cefixime trihydrate 125110-14-7

Cefixime trihydrate (FR-17027 trihydrate) is an antibiotic and a third generation cephalosporin antibiotic, useful for the treatment of a number of bacterial infections.

YN373992 5-Lipoxygenase-In-1 125235-15-6

5-Lipoxygenase-In-1 is a5-Lipoxygenaseinhibitor extracted from patent EP 331232 A2, table 4, compound example 4.10.

YN1710016 Tr-PEG4-OH 125274-16-0

Tr-PEG4-OH is a non-cleavable 4 unit PEGADClinker used in the synthesis of antibody-drug conjugates (ADCs).

YN321701 Bepotastine 125602-71-3

Bepotastine is a non-sedating, selective antagonist of the histamine 1 (H1) receptor that is indicated in allergic rhinitis, urticaria, and pruritus associated with skin disease.

YN320934 Tipelukast 125961-82-2

Tipelukast (KCA 757) is a sulfidopeptideleukotriene receptorantagonist, an orally bioavailable anti-inflammatory agent and used for the treatment of asthma.

YN370209 Atorvastatin lactone 125995-03-1

Atorvastatin lactone is a prodrug form of atorvastatin. Atorvastatin is an orally active3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA)reductase inhibitor.

YN482503 Siamenoside I 126105-12-2

Siamenoside I is one of the mogrosides that has several kinds of bioactivities.

YN251672 Ginsenoside Rg4 126223-28-7

Ginsenoside Rg4 is a major protopanaxatriol type ginsenoside isolated from the leaves ofPanax ginsengC. A. Meyer. The protopanaxatriol type ginsenosides (such as Ginsenoside Rg4) exhibits various biological activities including ant...

YN360365 (R)-(+)-Anatabine 126454-22-6

(R)-(+)-Anatabine is an less active R-enantiomer of Anatabine. Anatabine is a potentα4β2 nAChRagonist. Anatabine inhibitsNF-κBactivation loweramyloid-β (Aβ)production by preventing the β-cleavage of amyloid precursor prot...

YN321546 Ciclesonide 126544-47-6

Ciclesonide is a glucocorticoid used to treat obstructive airway diseases.

YN310371 KT5823 126643-37-6

KT5823, a selective the cGMP-dependent protein kinase (PKG) inhibitor with anKivalue of 0.23μM, it also inhibits PKA and PKC with Ki values of 10μM and 4μM, respectively. KT5823 is a staurosporine-related protei...

YN373496 N-Acetyl-Ser-Asp-Lys-Pro 127103-11-1

N-Acetyl-Ser-Asp-Lys-Pro, an endogenous tetrapeptide secreted by bone marrow, is a specific substrate for the N-terminal site ofACE.

YN330656 Chitohexaose hexahydrochlorid... 127171-88-4

Chitohexaose hexahydrochloride is a chitosan oligosaccharide with anti-inflammatory effect. Chitohexaose hexahydrochloride binds to the active sites ofTLR4 and inhibits LPS induced inflammation.

YN330657 Chitoheptaose heptahydrochlor... 127171-89-5

Chitoheptaose heptahydrochloride is a chitosan oligosaccharide with antioxidant, anti-inflammatory, antiapoptotic and cardioprotective activities. Chitoheptaose heptahydrochloride significantly enhances the growth and photosynthesis p...