YN480373 (Rac)-Telmesteine 127657-29-8

(Rac)-Telmesteine is aproteaseinhibitor and is thus a suitable enzyme stabilizer extracted from patent WO 2017220302 A1, compound II-1. (Rac)-Telmesteine can be used as an enzyme stabilizer in protease-containing detergents and ...

YN260095 Tr-PEG6-OH 127999-16-0

Tr-PEG6-OH is a non-cleavable 6 unit PEGADClinker used in the synthesis of antibody-drug conjugates (ADCs).

YN320826 Veliflapon 128253-31-6

Veliflapon (BAY X 1005; DG-031) is an orally active and selective5-lipoxygenase activating protein (FLAP)inhibitor. Veliflapon inhibits the synthesis of theleukotrienes B4 and C4.

YN321205 KB-5492 anhydrous 129200-10-8

KB-5492 anhydrous is a potent and selective inhibitor ofsigma receptor, inhibits specific [3H]1,3-di(2-tolyl)guanidine (DTG) binding to thesigma receptor with an IC50 of 3.15μM. KB-5492 anhydrous is an anti-ulcer agent.

YN370013 ICI 211965 129424-08-4

ICI 211965 (ZM-211965) is a selective and orally potent5-Lipoxygenase(5-LPO) inhibitor.

YN330270 MSA-2 129425-81-6

MSA-2, a potent and orally available non-nucleotideSTINGagonist, hasEC50s of 8.3 and 24μM for human STING isoforms WT and HAQ, respectively. MSA-2 shows antitumor activity and stimulates interferon-β secret...

YN440196 Rp-8-CPT-cAMPS 129735-01-9

Rp-8-CPT-cAMPS, a cAMP analog, is a potent and competitive antagonist of cAMP-induced activation of cAMP-dependentPKA I and II. Rp-8-CPT-cAMPS preferentially selects site A of RI compares to site A of R...

YN250110 Rifalazil 129791-92-0

Rifalazil (KRM-1648; ABI-1648), a rifamycin derivative, inhibits the bacterial DNA-dependentRNA polymerase and kills bacterial cells by blocking off the β-subunit in RNA polymerase. Rifalazil (KRM-1648; ABI-1648) i...

YN370975 Sampatrilat 129981-36-8

Sampatrilat (UK-81252) is a potent and orally activevasopeptidaseinhibitor ofACE and neutral endopeptidase (NEP). Sampatrilat inhibits C-domain ACE (Ki=13.8nM) 12.4-fold more potent than that for the N-domain (Ki=171.9n...

YN321584 Levocetirizine 130018-77-8

Levocetirizine (LCZ, (R)-Cetirizine), the R-enantiomer of cetirizine, is an antagonist of histamine H(1) receptor.

YN322101 Levocetirizine dihydrochlorid... 130018-87-0

Levocetirizine is the active R-enantiomer of cetirizine and represents a new second-generation histamine H1 antagonist.

YN483983 C-Reactive Protein (CRP)... 130348-99-1

C-Reactive Protein (CRP) 201-206 is the 201-206 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.

YN483992 C-Reactive Protein (CRP)... 130349-01-8

C-Reactive Protein (CRP) 77-82 is the 77-82 fragment of C-Reactive Protein. C-Reactive Protein (CRP), the prototypic marker of inflammation, is a cardiovascular risk marker and may promote atherogenesis.

YN321518 Bindarit 130641-38-2

Bindarit exhibits selective inhibition against monocyte chemotactic proteins MCP-1/CCL2, MCP-3/CCL7 and MCP-2/CCL8.

YN250523 Quinaldopeptin 130743-07-6

Quinaldopeptin, a quinomycin antibiotic isolated from the culture ofStreptoverticillium albumstrain, is highly active against Gram-positive bacteria and anaerobes and strongly cytotoxic against cultured B16 melanoma cells.

YN330621 Benzoylgomisin O 130783-32-3

Benzoylgomisin O isolated fromSchis and ra rubriflora, has inhibitory activity against15-LOX,COX-1 and COX-2enzymes and anti-inflammatory activity.

YN310363 Decursinol angelate 130848-06-5

Decursinol angelate is a cytotoxic and protein kinase C activating agent from the root of Angelica gigas.

YN350230 Cornuside 131189-57-6

Cornuside is a secoiridoid glucoside isolated from the fruit ofCornus officinalisSieb. et Zucc., which is a traditional oriental medicine for treating inflammatory diseases and invigorating blood circulation. Cornuside inhibits mast ...

YN481206 (3R,5S)-Atorvastatin sodium 131275-93-9

(3R,5S)-Atorvastatin sodium is an impurity of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids. Atorvastatin inhibits human SV-SMC proliferation...

YN483750 PLP 139-151 131334-43-5

PLP (139-151) is amino acid residue 139 to 151 of myelin proteolipid protein (PLP) used to induce experimental autoimmune encephalomyelitis (EAE).