YN330042 RP-54745 135330-08-4

RP-54745 is an inhibitor of macrophage stimulation and interleukin-1production, and a potential antirheumatic compound.

YN330654 Rehmapicrogenin 135447-39-1

Rehmapicrogenin, isolated from the root ofRehmannia glutinosa, exhibits potent anti-inflammatory effect by inhibiting iNOS, COX-2 and IL-6.

YN280026 Sulfosuccinimidyl oleate 135661-44-8

Sulfosuccinimidyl oleate (Sulfo-N-succinimidyl oleate) is a long chain fatty acid that inhibits fatty acid transport into cells. Sulfosuccinimidyl oleate is a potent and irreversible inhibitor ofmitochondrial respiratory chain. Sulfo...

YN321332 (R,R)-Palonosetron Hydroch... 135729-75-8

(R,R)-Palonosetron Hydrochloride is the active enantiomer of Palonosetron.

YN480118 Bamaquimast 135779-82-7

Bamaquimast (F 10126; L 0042) is a potent antiasthmatic drug.

YN483956 IGF-I (24-41) 135861-49-3

IGF-I (24-41) is amino acids 24 to 41 fragment of Insulin-like Growth Factor I (IGF-I). IGF-I is partly responsible for systemic GH activities although it possesses a wide number of own properties (anabolic, antioxidant, a...

YN483308 Isomucronulatol 7-O-glucosid... 136087-29-1

Isomucronulatol 7-O-glucoside is a flavonoid isolated from the roots ofA. membranaceus. Isomucronulatol 7-O-glucoside exhibits weak inhibitory effects on LPS-stimulated production IL-12 p40 in vitro and has potential anti-inflam...

YN370409 DPP-IV-IN-2 136259-18-2

DPP-IV-IN-2 is an inhibitor of bothdipeptidyl peptidase IV(DPIV) and DP8/9with IC50s of 0.1 and 0.95μM, respectively.

YN480042 Thiazolidinone-Derivatives-1 136272-75-8

Thiazolidinone-Derivatives-1 is an antiulcer agent which inhibits the secretion of gastric acid.

YN322070 LTD4 antagonist 1 136564-67-5

LTD4antagonist 1 is a potent, orally active antagonist ofleukotriene D4(LTD4) with a Ki of 0.57nM.

YN482562 Anemarsaponin E 136565-73-6

Anemarsaponin E is extracted fromAnemarrhena asphodeloidesBunge and has anti-inflammatory activity.

YN482561 Timosaponin BII 136656-07-0

Timosaponin BII is a steroid saponin found in the rhizomes ofAnemarrhena asphodeloides. Timosaponin BII has neuronal protective and anti-inflammatory effects and antioxidant property.

YN330009 Quiflapon 136668-42-3

Quiflapon (MK-591) is a selective and specific5-lipoxygenase-activating protein (FLAP)inhibitor with an IC50 of 1.6nM in a FLAP binding assay. Quiflapon is also a potent and orally activeLeukotriene biosynthesis (LT) i...

YN482822 Episyringaresinol 4'-O-β-D... 137038-13-2

Episyringaresinol 4'-O-β-D-glncopyranoside (compound 22), isolated fromAlhagi sparsifoliaShap, is a natural potential neuroinflammatory inhibitor.

YN481349 Pimecrolimus 137071-32-0

Pimecrolimus is an immunophilin ligand, which binds specifically to the cytosolic receptor, immunophilin macrophilin-12 (FKBP-12) a calcineurin inhibitor.

YN483976 Iα52 137756-45-7

Iα52 is a naturally processed peptide encompassed the residues 52-68 of the murine I-Eα chain and may contribute to selection of immature T cells.

YN484103 LLO (91-99) 137856-41-8

LLO (91-99) (Listeriolysin O (91-99)), an exotoxin, is a class I MHC-restricted T-cell epitopes of listeriolysin (LLO). LLO (91-99) is an essential antigen for induction of T-cell mediated immunity in vivo.

YN373989 L-689502 138483-63-3

L-689502 is a potent inhibitor ofHIV-l proteasewith an IC50 of 1nM.

YN310202 Bisindolylmaleimide VIII ... 138516-31-1

Bisindolylmaleimide VIII acetate (Ro 31-7549 acetate) is a potent and selectiveprotein kinase C (PKC)inhibitor with an IC50 of 158nM for rat brain PKC. Bisindolylmaleimide VIII acetate has IC50s of 53, 195, 163, 213...

YN360458 (R)-Lansoprazole 138530-94-6

Dexlansoprazole, the dextrorotatory enantiomer of lansoprazole, is a proton pump inhibitor (PPI) formulated to have dual delayed-release properties.