Chemical structure
Cat.No.
Product Name
CAS no.
Target
Etalocib (LY293111), an orally activeleukotriene B4receptorantagonist, inhibits the binding of[3H]LTB4, with a Ki of 25nM. Etalocib (LY293111) prevents LTB4-induced calcium mobilization with anlC50of 20nM. Etalocib (LY2...
YN480304 Amotosalen hydrochloride 161262-45-9
Amotosalen hydrochloride (S-59) is a light-activated, DNA-, RNA-crosslinking psoralen compound, which is used to neutralise pathogens.
YN481566 Heptamidine dimethanesulfonat... 161374-55-6
Heptamidine dimethanesulfonate (SBi4211 dimethanesulfonate) is a potent Pentamidine-related inhibitor of thecalcium-binding protein S100B(Kd=6.9μM), selectively kills melanoma cells with S100B over those without S100B. Heptami...
YN360606 Esomeprazole potassium salt 161796-84-5
Esomeprazole potassium salt ((S)-Omeprazole potassium salt) is a potent and orally active proton pump inhibitor and reduces acid secretion through inhibition of theH+, K+-ATPasein gastric parietal cells. Esomeprazole potassium ...
YN481278 Acid secretion-IN-1 161958-62-9
Acid secretion-IN-1 is a polycyclic compound extracted from patent WO2018024188A1, Compound Example 17.4. Acid secretion-IN-1 is synthesized and used in the IDO inhibitor synthetic experiment.
YN330341 Rofecoxib 162011-90-7
Rofecoxib is a COX-2 inhibitor with IC50 of 18 nM.
SC-58125 is a potent and selective inhibitor ofcyclooxygenase 2 (COX-2), with an IC50 of 0.04μM. SC-58125 exhibits antitumor activity in vitro and in vivo, and it also can inhibit edema at the inflammatory site and is ana...
YN300018 RWJ 50271 162112-37-0
RWJ 50271 is an selective inhibitor oflymphocyte function-associated antigen-1/intercellular adhesion molecule-1(LFA-1/ICAM-1)interaction with an IC50 of 5.0μM (HL60 cells). RWJ 50271 inhibits LFA-1/ICAM-1-mediated...
YN320423 Fingolimod 162359-55-9
Fingolimod is a sphingosine 1-phosphate receptor modulator used for the treatment of relapsing-remitting multiple sclerosis.
YN320528 Fingolimod hydrochloride 162359-56-0
Fingolimod (FTY720) HCl is a S1P antagonist with IC50 of 0.033 nM in K562, and NK cells.
YN372304 Roflumilast 162401-32-3
Roflumilast is a selective inhibitor of PDE4 with IC50 of 0.2-4.3 nM in a cell-free assay.
AT-56 is an orally active and selective inhibitor of lipocalin-type prostaglandin (PG) D synthase (L-PGDS) with Ki of 75 μM and IC50 of 95 μM.
HQL-79, a potent, selective and orally active humanhematopoietic prostagl and in D synthase (H-PGDS)inhibitor, highly selectively inhibits the synthesis of PGD2, and acts as an anti-allergic agent, with aKdof 0.8μM and ...
YN482812 Polygalasaponin V 162857-65-0
Polygalasaponin V is a triterpenoid saponin isolated from the aerial parts ofPolygala japonica.Polygala japonicahas been a folk medicine herb used as expectorant, anti-inflammatory, antibacterial and antidepressant agents in the south...
YN373200 Polygalaxanthone III 162857-78-5
Polygalaxanthone III can significantly inhibit chlorzoxazone 6-hydroxylation catalyzed by CYP2E1.
YN483791 C-telopeptide 162929-64-8
C-telopeptide, a cross-linked peptide of type I collagen, is released during bone resorption and has been correlated with bone mineral density (BMD).
YN481430 Teriflunomide 163451-81-8
Teriflunomide is the active metabolite of leflunomide, an approved therapy for rheumatoid arthritis. It inhibitspyrimidine synthesis and therefore potently decreases T cell and B cell proliferation.
YN483924 AMARA peptide 163560-19-8
AMARA peptide is a substrate for SIK and AMPK.
YN321235 Cangrelor tetrasodium 163706-36-3
Cangrelor is a potent, competitive P2Y12 receptor inhibitor that is administered by intravenous infusion and rapidly achieves near complete inhibition of ADP-induced platelet aggregation.
YM 90709 is a novel IL-5 inhibitor which selectively blocks the binding of IL-5 to the IL-5 receptor (IL-5R).
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