YN330703 SC-236 170569-86-5

SC-236 is an orally activeCOX-2specific inhibitor (IC50= 10nM) and aPPARγagonist. SC-236 supresses activator protein-1 (AP-1) through c-Jun NH2-terminal kinase. SC-236 exerts anti-inflammatory effects by suppressing ...

YN330160 Desmethyl Celecoxib 170569-87-6

Desmethyl Celecoxib (compound 3b), an analog of Celecoxib with the optimal yield of 75%, is a selective inhibitor of cyclooxygenase-2 (COX-2) with anti-inflammatory activities.

YN330165 Mavacoxib 170569-88-7

Mavacoxib is a selective, long-acting cyclooxygenase-2 (COX-2) inhibitor. Mavacoxib is a novel nonsteroidal anti-inflammatory drug (NSAID).

YN320136 CHPG 170846-74-9

CHPG is a selectivemGluR5agonist, and attenuates SO2-induced oxidative stress and inflammation throughTSG-6/NF-κBpathway in BV2 microglial cells. CHPG protects against traumatic brain injury (TBI) in vitro and ...

YN321902 SLIGRL-NH2 171436-38-7

SLIGRL-NH2 (Protease-Activated Receptor-2 Activating Peptide) is an agonist of Protease-Activated Receptor-2 (PAR-2).

YN410110 Myrislignan 171485-39-5

Myrislignan, a lignan isolated from Myristica fragrans Houtt, possesses anti-inflammatory activities. Myrislignan inhibits interleukin-6 (IL-6) and tumour necrosis factor-α (TNF-α). Myrislignan significantly inhibits the express...

YN360103 Ilaprazole 172152-36-2

Ilaprazole is a new proton pump inhibitor (PPI) used in the treatment of dyspepsia, peptic ulcer disease (PUD), gastroesophageal reflux disease (GORD/GERD) and duodenal ulcer. It inhibits H+/K+-ATPase with an IC50 of ...

YN360895 Ilaprazole sodium 172152-50-0

Ilaprazole sodium is the sodium salt form of ilaprazole, which is a proton pump inhibitor.

YN321661 Acrivastine D7 172165-56-9

Acrivastine D7 (BW825C D7) is a deuterium labeled Acrivastine. Acrivastine is a short acting histamine 1 receptor antagonist.

YN251868 SMAP-29 172485-26-6

SMAP-29, a promisingantiinfectiveagent, is a broad spectrum antibacterial and antifungal α-helical cathelicidin-derived peptide. SMAP-29 acts by permeabilizing bacterial membranes and inducing remarkable changes in the surface ...

YN371549 Varespladib 172732-68-2

Varespladib (LY315920) is a potent and selective human non-pancreatic secretory phospholipase A2 (hnsPLA) inhibitor with IC50 of 7 nM. Phase 3.

YN372441 Varespladib methyl 172733-08-3

Varespladib methyl (A-002; LY333013) is a selective inhibitor of group II secretory phospholipase A2 (PLA2).

YN371550 Varespladib sodium 172733-42-5

Varespladib sodium (LY315920 sodium) is a potent and selectivegroup IIA, secretory phospholipase A2(sPLA2)inhibitor with an IC50 of 9nM. Varespladib sodium exhibits the significant inhibitory effect onsPLA2activity in ser...

YN483716 Epimedin K 174286-13-6

Epimedin K (Korepimedoside B), a flavonol glycoside, is isolated from the aerial parts ofEpimedium koreanumNakai.Epimedium koreanumNakai is a famous Chinese herbal medicine for the research of impotence, osteoporosis, immune suppre...

YN483090 Tsugaric acid A 174391-64-1

Tsugaric acid A can significantly inhibit superoxide anion formation. Tsugaric acid A also protects human keratinocytes against damage induced by ultraviolet B (UV B) light. Tsugaric acid A can protect keratinocytes from photodama...

YN484166 Rituximab 174722-31-7

Rituximab is an anti-CD20 chimeric monoclonal antibody used to treat certain autoimmune diseases and types of cancer.

YN300039 Tonabersat 175013-84-0

Tonabersat (SB-220453) is agap-junctionmodulator. Tonabersat prevents inflammatory damage in the central nervous system .

YN373988 CMI977 175212-04-1

CMI977 is a potent5-Lipoxygenase(5-LO) inhibitor.

YN482998 16α-Hydroxydehydrotrametenol... 176390-66-2

16α-Hydroxydehydrotrametenolic acid is a triterpene Acid in fermented mycelia of edible fungusPoria cocos.

YN410112 Sauchinone 177931-17-8

A lignan that has numerous effects on isolated cells and cardioprotective effects in vivo