Trametinib
Cat. No. :YN350063
CAS No. :871700-17-3
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5mg
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Product Name: | Trametinib |
CAS NO.: | 871700-17-3 |
Chemical Name: | |
Synonyms: | JTP-74057 |
Molecular Weight: | 615.39 |
Molecular Formula: | C₂₆H₂₃FIN₅O₄ |
SMILES: | CC(NC1=CC=CC(N(C2=O)C(C(C(N2C3CC3)=O)=C(N4C)NC5=CC=C(C=C5F)I)=C(C4=O)C)=C1)=O |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | Trametinib (GSK1120212) is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assays, no inhibition of the kinase activities of c-Raf, B-Raf, ERK1/2. |
IC50&Target: | |
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In Vivo: | |
Clinical Trial: | |
Solvent & Solubility: | |
References: |
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