Ro 5126766
Cat. No. :YN350185
CAS No. :946128-88-7
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order@ubiochem.com| Product Name: | Ro 5126766 |
| CAS NO.: | 946128-88-7 |
| Chemical Name: | |
| Synonyms: | |
| Molecular Weight: | 471.46 |
| Molecular Formula: | C₂₁H₁₈FN₅O₅S |
| SMILES: | O=S(NC)(NC1=NC=CC(CC2=C(C)C3=CC=C(OC4=NC=CC=N4)C=C3OC2=O)=C1F)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Ro 5126766 (CH5126766) is a first-in-class dualMEK/RAFinhibitor that allosterically inhibitsBRAFV600E,CRAF,MEK, and BRAF(IC50: 8.2, 56, 160nM, and 190nM, respectively). |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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