Trametinib (DMSO solvate)
Cat. No. :YN350064
CAS No. :1187431-43-1
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order@ubiochem.com| Product Name: | Trametinib (DMSO solvate) |
| CAS NO.: | 1187431-43-1 |
| Chemical Name: | |
| Synonyms: | GSK1120212, JTP-74057, Mekinist |
| Molecular Weight: | 693.53 |
| Molecular Formula: | C₂₈H₂₉FIN₅O₅S |
| SMILES: | CN1C(C(C)=C(N(C(N(C2=O)C3CC3)=O)C4=CC=CC(NC(C)=O)=C4)C2=C1NC5=CC=C(C=C5F)I)=O.CS(C)=O |
| Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
| Transportation: | Room temperature in continental US; may vary elsewhere. |
| Description: | Trametinib (GSK1120212, JTP-74057, Mekinist) DMSO solvate is a highly specific and potent MEK1/2 inhibitor with IC50 of 0.92 nM/1.8 nM in cell-free assay. Trametinib activates autophagy and induces apoptosis. |
| IC50&Target: | |
| In Vitro: | |
| In Vivo: | |
| Clinical Trial: | |
| Solvent & Solubility: | |
| References: |
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