BI-847325
Cat. No. :YN350192
CAS No. :1207293-36-4
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5mg
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Product Name: | BI-847325 |
CAS NO.: | 1207293-36-4 |
Chemical Name: | |
Synonyms: | |
Molecular Weight: | 464.56 |
Molecular Formula: | C₂₉H₂₈N₄O₂ |
SMILES: | O=C(NCC)C#CC1=CC(NC/2=O)=C(C=C1)C2=C(NC3=CC=C(CN(C)C)C=C3)/C4=CC=CC=C4 |
Storage: | Please store the product under the recommended conditions in the Certificate of Analysis. |
Transportation: | Room temperature in continental US; may vary elsewhere. |
Description: | BI-847325 is an orally bioavailable, and selective dual MEK/Aurora kinase inhibitor with IC50 of 3 nM, 25 nM, 15 nM, 25 nM, and 4 nM for Xenopus laevis Aurora B, human Aurora A and Aurora C, as well as human MEK1 and MEK2, respectively. Phase 1. |
IC50&Target: | |
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Clinical Trial: | |
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References: |
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