YN372529 E-5324 141799-76-0

E-5324 is potent inhibitor of acyl-CoA:cholesterol acyltransferase (ACAT) with IC50s of 44 to 190nM.

YN370127 L-690488 142523-14-6

L-690488 is a prodrug of L-690330 and is a selectiveinositol monophosphatase (IMPase)inhibitor. L-690488 has more effective cell penetration than L-690330.

YN484118 Renin FRET Substrate I 142988-22-5

Renin FRET Substrate I is a substrate of human renin. Renin FRET Substrate I is designed to incorporate the renin cleavage site that occurs in the N-terminal peptide of human angiotensinogen.

YN483463 Quercetin 3-O-β-D-(6''-p-c... 143061-65-8

Quercetin 3-O-β-D-(6''-p-coumaroyl)glucopyranosyl(1→2)-α-L-rhamnopyranoside (Quercetin-3-O-[2-O-(6-O-p-hydroxyl-E-coumaroyl)-D-glucosyl]-(1→2)-L-rhamnoside) is one of the major antioxidants ofGinkgo bilobaleaves.

YN483963 Axltide 143364-95-8

Axltide is based on the mouse Insulin receptor substrate 1 (amino acid 979-989). Axltide is a substrate for Axl, DDR2, Mst1, and JAK2 kinases.

YN374310 2-Aminopyrimidin-5-ol 143489-45-6

2-Aminopyrimidin-5-ol is an endogenous metabolite.

YN372814 Creatinine-D3 143827-20-7

Creatinine-D3 (NSC13123-D3) is a deuterium labeled Creatinine. Creatinine is a break-down product of creatine phosphate in muscle.

YN372189 Febuxostat 144060-53-7

Febuxostat is a selective xanthine oxidase inhibitor with Ki of 0.6 nM.

YN483784 Xenin 144092-28-4

Xenin is a 25-amino acid peptide initially isolated from human gastric mucosa. Xenin is a gut hormone that can reduce food intake.

YN373096 Licochalcone C 144506-14-9

Licochalcone C could inhibitα-glucosidase, with IC50s of <100nM and 92.43μM for α-glucosidase and protein tyrosine phosphatase 1B (PTP1B), respectively.

YN410137 Licochalcone D 144506-15-0

Licochalcone D, a flavonoid compound mainly existing in the root ofGlycyrrhiza inflate, is a potent inhibitor ofNF-kappaB (NF-κB) p65. Licochalcone D possesses antioxidant, anti-inflammatory, anti-cancer properties.

YN373323 Oxyresveratrol 3'-O-β-D-gl... 144525-40-6

Oxyresveratrol 3'-O-β-D-glucopyranoside is a phenolic compound isolated fromMorus nigraroot and is an effectivetyrosinaseinhibitor with an IC50 of 1.64μM.

YN320256 YM022 145084-28-2

YM022 is a highly potent, selective and orally activegastrin/cholecystokinin (CCK)-B receptor (CCK-BR)antagonist. YM022 shows theKivalues of 68 pM and 63nM for CCK-B and CCK-A receptor, respectively. YM022 ca...

YN320406 L-692429 145455-23-8

L-692429 (MK-0751) is a benzolactam derivative and a nonpeptidylgrowth hormone secretagogue (GHS)agonist. L-692429 binds toG protein-coupled receptor with a Ki of 63nM.

YN360616 Mitiglinide Calcium 145525-41-3

Mitiglinide Calcium (KAD-1229; S21403) is anATP-sensitive K+(KATP) channelantagonist. Mitiglinide Calcium is highly specific to the Kir6.2/SUR1 complex (the pancreatic beta-cell KATPchannel). Mitiglinide Calcium ca...

YN370183 ACAT-IN-1 cis isomer 145961-79-1

ACAT-IN-1 cis isomer is a potentACATinhibitor with an IC50 of 100nM.

YN290158 Leriglitazone 146062-44-4

Leriglitazone (Hydroxypioglitazone), a metabolite of pioglitazone. Leriglitazone (Hydroxypioglitazone) PioOH is aPPARγagonist, stabilizes the PPARγ activation function-2 (AF-2) co-activator binding surface and enhances ...

YN370742 L-Glyceric acid sodium 146298-95-5

L-Glyceric acid sodium is a mainly urinary metabolite accumulating in rare inherited metabolic disease L-glyceric aciduria. L-Glyceric acid sodium can be used to diagnose primary hyperoxaluria type 2 (PH2). L-Glyceric acid sodium e...

YN482314 Dabcyl acid, SE 146998-31-4

Dabcyl acid, SE is the amino-reactive form of Dabcyl acid (DABCYL), and widely used to prepare a variety of FRET-based probes that contain DABCYL.

YN360626 Rosuvastatin Calcium 147098-20-2

Rosuvastatin Calcium is a competitive inhibitor of HMG-CoA reductase with IC50 of 11 nM in a cell-free assay.