YN373214 Dencichine 5302-45-4

Dencichin is a non-protein amino acid originally extracted fromPanax notoginseng, and can inhibitHIF-prolyl hydroxylase-2 (PHD-2)activity.

YN360210 QX-314 chloride 5369-03-9

QX-314 chloride directly activates and permeates the human isoforms of TRPV1 and TRPA1 to induce inhibition of sodium channels.

YN360393 ML204 5465-86-1

ML204 is a novel, potent, and selective TRPC4 channel inhibitor with apparent IC50 values of about 1 μM in fluorescent intracellular Ca2+ assays and about 3 μM in whole-cell voltage clamp experiments. It exhibits some selectiv...

YN320588 Iprindole 5560-72-5

Iprindole, a tricyclic indole antidepressant, is a weak inhibitor of the uptake of noradrenaline and 5-HT.

YN321523 Betahistine dihydrochloride 5579-84-0

Betahistine is a histamine H3 receptor inhibitor with IC50 of 1.9 μM.

YN380083 Chlorpyrifos-oxon 5598-15-2

Chlorpyrifos-oxon, an active metabolite of Chlorpyrifos, is a potent phosphorylating agent that potently inhibitsAChE. Chlorpyrifos-oxon can induce cross-linking between subunits of tubulin and disrupt microtubule function.

YN360964 (-)-Securinine 5610-40-2

(-)-Securinine is plant-derived alkaloid and also a GABAA receptor antagonist.

YN321666 Benzetimide hydrochloride 5633-14-7

Benzetimide hydrochloride is a muscarinic acetylcholine receptor antagonist.

YN321439 Oxybutynin 5633-20-5

Oxybutynin is a competitive antagonist of the M1, M2, and M3 subtypes of the muscarinic acetylcholine receptor, used to relieve urinary and bladder difficulties.

YN482011 Acetophenazine dimaleate 5714-00-1

Acetophenazine dimaleate is an antipsychotic agent, effective in anxious depression.

YN370779 5-Hydroxydopamine hydrochlori... 5720-26-3

5-Hydroxydopamine is a naturally occurring amine in human urine.

YN380138 Salsolidine 5784-74-7

Salsolidine is a tetrahydroisoquinoline alkaloid, acts as a stereoselective competitiveMAO Ainhibitor.

YN320875 Clozapine 5786-21-0

Clozapine is an atypical antipsychotic drug by acting as a 5-HT antagonist, used in the treatment of schizophrenia.

YN321672 Cyclopentolate hydrochloride 5870-29-1

Cyclopentolate is an antagonist of muscarinic acetylcholine receptors with Ki values of 1.62, 27.5, and 2.63 nM for M1, M2, and M3 receptors, respectively.

YN360714 Proparacaine Hydrochloride 5875-06-9

Proparacaine HCl is a voltage-gated sodium channels antagonist with ED50 of 3.4 mM.

YN483031 Meranzin (hydrate) 5875-49-0

Meranzin hydrate, an absorbed bioactive compound from the Traditional Chinese Medicine (TCM) Chaihu-Shugan-San (CSS), possess anti-depression and anti-atherosclerosis effects.

YN321482 Atropine sulfate monohydrate 5908-99-6

Atropine sulfate monohydrate is a competitive antagonist for the muscarinic acetylcholine receptor, used to decrease the production of saliva and secretions of the airway prior to surgery.

YN321759 Nimbin 5945-86-8

Nimbin is a intermediate limonoid isolated fromAzadirachta. Nimbin preventstauaggregation and increases cell viability. Nimbin is effective inhibits theenvelope protein of dengue virus. Nimbin has anti-inflammatory, antipyretic, anti...

YN360969 Podocarpic acid 5947-49-9

Podocarpic acid is a natural product, which has the best all-round positive effect and acts as a novelTRPA1activator.

YN250394 Piperlonguminine 5950-12-9

Piperlonguminine is an alkaloid amide isolated from thePiperspecies. Piperlonguminine shows various biological properties, including anti-inflammatory, antitumor, neuroprotective, anti-platelet, anti-melanogenic, antifungal and antibac...