YN360637 NMDA 6384-92-5

NMDA is a specific agonist forNMDA receptormimicking the action of glutamate, the neurotransmitter which normally acts at that receptor.

YN251290 Amodiaquine dihydrochloride d... 6398-98-7

Amodiaquine is a potent, non-competitive inhibitor of histamine N-methyl transferase with estimated Ki of 18.6 nM. It is also used as an antimalarial and anti-inflammatory agent.

YN482375 Tetrahydropapaverine hydrochl... 6429-04-5

Tetrahydropapaverine, one of the TIQs and an analogue of salsolinol and tetrahydropapaveroline, has been reported to have neurotoxic effects on dopamine neurons.

YN321441 Chlorprothixene hydrochloride 6469-93-8

an inhibitor of AmpC Beta-Lactamase

YN321737 Tetrahydroalstonine 6474-90-4

Tetrahydroalstonine, a indole alkaloid isolated from the fruits ofRhazya stricta, is a selectivealpha 2-adrenoceptorantagonist.

YN330650 Norgestrel 6533-00-2

Norgestrel is synthetic steroidal progestin that is used in combination with ethinyl estradiol for oral contraception. It also has strong neuroprotective activity.

YN360998 Cirsimaritin 6601-62-3

Cirsimaritin binds weakly to the benzodiazepine site onGABAAreceptors, with antidepressant, anxiolytic and antinociceptive activities.

YN440429 6-Demethoxytangeretin 6601-66-7

6-Demethoxytangeretin is a citrus flavonoid isolated fromCitrus depressa. 6-Demethoxytangeretin exerts anti-inflammatory activity and anti-allergic activity, suppresses production and gene expression of interleukin-6 in human mast ce...

YN321645 Proglumide 6620-60-6

Proglumide is a nonpeptide and orally activecholecystokinin (CCK)-A/B receptorsantagonist. Proglumide selective blocksCCK’s effects in the central nervous system (CNS). Proglumide has ability to inhibit gastric secretion a...

YN350271 Pamoic acid disodium 6640-22-8

Pamoic acid disodium is a potentGPR35agonist with an EC50 value of 79nM. Pamoic acid disodium inducesGPR35internalization and activatesERK1/2withEC50values of 22nM and 65nM, respectively. Pamoic acid disodium potently...

YN373338 Dihydrorotenone 6659-45-6

Dihydrorotenone, a natural pesticide, is a potentmitochondrialinhibitor. Dihydrorotenone probably induces Parkinsonian syndrome. Dihydrorotenone induces human plasma cellapoptosisby triggering endoplasmic reticulum stress and activati...

YN321730 Jatrorrhizine chloride 6681-15-8

Jatrorrhizine hydrochloride can inhibit the proliferation and neovascularization of C8161 metastatic melanoma cells with low toxicity, suggests that jatrorrhizine hydrochloride is a potential new antimelanoma drug candidate. Jatrorrhizin...

YN360050 gamma-DGG 6729-55-1

gamma-DGG is a competitive AMPA receptorblocker.

YN482684 Kaurenoic acid 6730-83-2

Kaurenoic acid has cytotoxic and embryotoxic effects. Kaurenoic acid has anti-inflammatory potential in acetic acid-induced colitis, decreases in MDA level, an indicator of lipoperoxidation in colon tissue. Kaurenoic acid exerts a u...

YN372856 Teprenone 6809-52-5

Teprenone, an acylic polyisoprenoid, that is known as tetraprenylacetone or geranylgeranylacetone, is an anti-ulcer drug, clinically used for gastritis.

YN482421 Deltaline 6836-11-9

Deltaline is a diterpenoid alkaloid and isolated from plants of the genusDelphinium delavayiFranch. Deltaline itself has analgesic properties, and plants of the genus Delphinium delavayi Franch have also been therapeutically used ...

YN360945 Xanthoplanine 6872-88-4

Xanthoplanine, isolated from theroot ofXylopia parviflora, fully inhibits the EC50ACh responses of both alpha7 and alpha4beta2 nACh receptors with estimatedIC50 values of 9μM (alpha7) and 5μM (alpha4beta2).

YN380223 Epiberberine 6873-09-2

A quantitative high throughput screen for small molecules that induce DNA re-replication in MCF 10a normal breast cells.

YN370104 D-Glutamic acid 6893-26-1

D-glutamic acid, an enantiomer of L- glutamic acid, is widely used in pharmaceuticals and foods.

YN280099 Genipin 6902-77-8

Genipin is an active aglycone derived from an iridoid glycoside called geniposide, which is found in the fruit of Gardenia jasminoides Ellis.