YN380010 LM22A-4 37988-18-4

LM22A-4 is a specific agonist oftyrosine kinase receptor B, used for neurological disease research.

YN1730123 Nitrobenzylthioinosine 38048-32-7

Nitrobenzylthioinosine is anENT1 transporterinhibitor that binds toENT1 transporterwith high affinity. Nitrobenzylthioinosine is a photoaffinity probe for adenosine uptake sites in brain. Nitrobenzylthioinosine can cross the blood-...

YN481187 Palmitoyl glutamic acid 38079-66-2

Palmitoyl glutamic acid (N-Palmitoyl-L-glutamic acid) is an acyl amino acid with neuroprotective effects. Palmitoyl glutamic acid is used as cosmetic material.

YN380315 7,8-Dihydroxyflavone 38183-03-8

7,8-Dihydroxyflavone acts as a potent and selective small-molecule agonist of the TrkB receptor (Kd ≈ 320 nM), the main signaling receptor of brain-derived neurotrophic factor (BDNF).

YN380228 Aloenin 38412-46-3

Aloenin (Aloenin A) is a class of anthraquinones isolated fromAloearborescens. Aloenin has potent peroxyl radical-scavenging activities and moderate inhibitory active onβ-secretase (BACE).

YN371187 m-Tyramine hydrobromide 38449-59-1

m-Tyramine hydrobromide is an endogenous trace amine neuromodulator. m-Tyramine hydrobromide has effects on theadrenergic and dopaminergicreceptor.

YN330100 N-Acetylcysteine amide 38520-57-9

N-acetylcysteine amide is a membrane penetrating antioxidant with anti-inflamatory activity through regulation of activation of NF-κB and HIF-1α as well as modulation of ROS.

YN330425 Carbidopa monohydrate 38821-49-7

Carbidopa ((S)-(-)-Carbidopa) monohydrate, a peripheraldecarboxylaseinhibitor, can be used for the research of Parkinson's disease. Carbidopa monohydrate is a selectivearyl hydrocarbon receptor (AhR)modulator. Carbidopa monohydrate ...

YN480282 Furobufen 38873-55-1

Furobufen, an anti-inflammatory agent, produces antiarthritic, antipyretic effects. Furobufen has an analgesic effect in inflamed tissue.

YN483063 Gelsevirine 38990-03-3

Gelsevirine is the major alkaloid inGelsemium eleganswith potent anxiolytic effects. The anxiolytic mechanism of Gelsevirine may be involved in the agonist action of the glycine receptor in the brain. Gelsevirine has anti-proliferation...

YN330548 Picroside II 39012-20-9

Picroside II is the main active ingredient in iridoid glycosides, which is the principal component of Picrorrhiza kurroa Royle. It has antioxidant, anti-inflammatory, immune regulatory, anti-virus and other pharmacological acti...

YN480772 Fenpropathrin 39515-41-8

Fenpropathrin is a synthetic pyrethroid insecticide in agriculture. Fenpropathrin may induces parkinsonian symptoms progressively.

YN370838 Etilevodopa hydrochloride 39740-30-2

Etilevodopa (L-Dopa ethyl ester) hydrochloride, an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa hydrochloride is used for the trea...

YN280062 TFEB activator 1 39777-61-2

TFEB activator 1 is an orally effective, mTOR-independent activator ofTFEB. TFEB activator 1 significantly promotes the nuclear translocation of Flag-TFEB with an EC50 of 2167nM. TFEB activator 1 enhancesautophagy...

YN1710008 Adenosine A1 receptor activa... 40312-34-3

Adenosine A1 receptor activator T62 is an allosteric enhancer ofadenosine A1 receptor. Adenosine A1 receptor activator T62 produces antinociception in animal models of acute pain and also reduces hypersensitivity in models of infla...

YN1730009 Cirazoline hydrochloride 40600-13-3

Cirazoline hydrochloride (LD 3098 hydrochloride) is a potent competitive fullα1A-adrenergic receptor (α1A-AR)agonist (Ki=120nM) and only a partial agonist at α1B-AR (Ki= 960nM) and α1D-AR (Ki=660nM).

YN480239 DSP-4 hydrochloride 40616-75-9

DSP-4 hydrochloride (Neurotoxin DSP 4 hydrochloride) is a highly selective neurotoxin and readily passes the blood-brain barrier with neurotoxic effects on noradrenergic neurons of adult and developing rats, can be used for the t...

YN380060 RX 67668 40709-76-0

RX 67668 is a potentcholinesteraseinhibitor with an IC50 of 5μM for bothacetylcholinesterase (AChE) and butyrylcholinesterase. RX 67668 can reverse the neuromuscular blockade induced by D-tubocurarine. RX 67668 is a muscle re...

YN321665 Bemesetron 40796-97-2

Bemesetron (MDL 72222) is a selective5-HT3receptorantagonist with an IC50 of 0.33nM. Neuroprotective effect.

YN380235 Timosaponin AIII 41059-79-4

Timosaponin A3 triggers liver injury through inducing ROS generation and suppressing the expression of BA transporters. Timosaponin A3 has selectively cytotoxic for cancer versus normal cells, the selective cytotoxic properties of...