YN360173 Asoxime dichloride 34433-31-3

Asoxime dichloride (HI-6) is an antagonist toacetylcholine receptors (AChRs)including the nicotinic receptor, α7 nAChR. Asoxime dichloride involves in modulating immunity response. Asoxime dichloride (HI-6) can be used as an a...

YN321490 Loperamide hydrochloride 34552-83-5

Loperamide HCl is a selective μ-opioid receptor agonist opioid with Ki of 3.3 nM, 15-fold and 350-fold selective over the δ subtype and the κ subtype of the opioid receptor, used against diarrhea resulting from gastroenteritis or in...

YN321562 Urapidil 34661-75-1

Urapidil is an antihypertensive drug acting as an α1 adrenoreceptor antagonist and a 5-HT1A agonist.

YN270545 Incensole Acetate 34701-53-6

Incensole acetate, isolated from Boswellia Resin, is a novel anti-inflammatory compound that inhibits NF-κB activation.

YN483131 Isopropylidenylacetyl-marmesi... 35178-20-2

Isopropylidenylacetyl-marmesin ((±)-Prantschimgin) is a coumarin isolated from the roots ofF. bracteata.

YN482831 Hirsuteine 35467-43-7

Hirsuteine is an indole alkaloid extracted fromUncaria genus. Hirsuteine non-competitively antagonizes nicotine-mediated dopamine release by blocking ion permeation through nicotinic receptor channel complexes.

YN380053 Azamethiphos 35575-96-3

Azamethiphos is an organophosphate (OP) pesticide used to combat sea lice infestations in farmed salmonids.

YN483893 Pressinoic Acid 35748-51-7

Pressinoic Acid is a synthetic hexapeptide with potent corticotrophin-releasing activity. Pressinoic Acid is also anoxytocininhibitor; it induces maternal behavior.

YN280147 Onjisaponin B 35906-36-6

Onjisaponin B is a natural product derived fromRadix Polygalae. Onjisaponin B enhances autophagy and accelerates the degradation of mutant α-synuclein and huntingtin in PC-12 cells, and exbibits potential therapeutic effects ...

YN321320 Talipexole dihydrochloride 36085-73-1

Talipexole dihydrochloride (B-HT 920 dihydrochloride) is a dopamine D2 receptor agonist, α2-adrenoceptor agonist and 5-HT3 receptor antagonist, which displays antiParkinsonian activity.

YN321697 Dimemorfan phosphate 36304-84-4

an antagonist of the estrogen receptor alpha (ER-alpha) signaling pathway

YN1730082 N6-Cyclohexyladenosine 36396-99-3

N6-Cyclohexyladenosine is a selective A1 receptor agonist (EC50 = 8.2nM).

YN380250 N-p-trans-Coumaroyltyramine 36417-86-4

N-p-trans-Coumaroyltyramine is a cinnamoylphenethyl amide isolated frompolygonum hyrcanicum, acts as an acetylcholinesterase (AChE) inhibitor with an an IC50 of 122μM. N-p-trans-Coumaroyltyramine exhibits anti-trypanosomal activi...

YN320171 Pargolol hydrochloride 36902-82-6

Pargolol hydrochloride is aβ adrenergic receptorantagonist.

YN360254 Icilin 36945-98-9

Icilin (AG-3-5) is an agonist of nonselective cation channelTRPM8, with antiproliferative activity. Icilin activated currents only in wild type TRPM8 and in the presence of Ca2+. Icilin can induce G1 arrest in prostate canc...

YN482930 Oroxylin A-7-O-glucuronide 36948-76-2

Oroxylin A-7-O-glucuronide (Oroxyloside; Oroxylin A-7-O-β-D-glucuronide) is a flavonoid glucuronide isolated from the dried root ofScutellaria baicalensis, withprolyl oligopeptidase (POP)inhibitory activity.

YN370837 Etilevodopa 37178-37-3

Etilevodopa (L-Dopa ethyl ester), an ethyl-ester prodrug of Levodopa, is rapidly hydrolyzed to Levodopa and ethanol by nonspecific esterases in the gastrointestinal tract. Etilevodopa is used for the treatment of Parkinson disease ...

YN372951 Zaprinast 37762-06-4

Zaprinast (M&B 22948) is an inhibitor of cGMP-selectivePhosphodiesterases(PDEs). Zaprinast is aG protein-coupled receptor (GPR) 35agonist which activates rat GPR35 strongly and activates human GPR35 moderately. Zapri...

YN480025 W-2429 37795-69-0

W-2429 is a non-narcotic analgesic agent.

YN270080 Ro 08-2750 37854-59-4

Ro 08-2750 is a non-peptide and reversiblenerve growth factor (NGF)inhibitor which binds to NGF, and with an IC50 of ~ 1 µM. Ro 08-2750 inhibits NGF binding to p75NTRselectively over TRKA. Ro 08-2750 is a selectiv...