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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN373377 Secologanoside 59472-23-0

    Secologanoside is a triterpenoid isolated fromPoraqueiba sericea, weakly inhibitselastasewith an IC50 of 164 μg/mL. Secologanoside is moderate cytotoxic to fibroblasts.

  • YN380201 Citalopram hydrobromide 59729-32-7

    Citalopram HBr, an antidepressant, is an orally administered selective serotonin reuptake inhibitor (SSRI) with IC50 of 1.8 nM.

  • YN370879 Halopemide 59831-65-1

    Halopemide is a potentphospholipase D (PLD)inhibitor, with IC50s of 220 and 310nM for human PLD1 and PLD2, respectively. Halopemid is adopamine receptorsantagonist, and acts a psychotropic agent.

  • YN373328 Glabrene 60008-03-9

    Glabrene, an isoflavene derived from licorice root, shows estrogen-like activity. Glabrene is atyrosinaseinhibitor with an IC50 of 3.5μM.

  • YN321933 [Met5]-Enkephalin, amide 60117-17-1

    [Met5]-Enkephalin, amide is an agonist forδ opioid receptorsas well as putativeζ (zeta) opioid receptors.

  • YN321935 [Leu5]-Enkephalin, amide 60117-24-0

    [Leu5]-Enkephalin, amide is aδ opioid receptoragonist.

  • YN360718 Gabapentin hydrochloride 60142-95-2

    Gabapentin HCl is a GABA analogue, used to treat seizures and neuropathic pain.

  • YN360717 Gabapentin 60142-96-3

    Gabapentin is a GABA analogue, used to treat seizures and neuropathic pain.

  • YN480187 Sulforhodamine 101 60311-02-6

    Sulforhodamine 101 (SR101) is an amphoteric rhodaminered fluorescent dye(excitation/emission: 586/605nM). Sulforhodamine 101 is used extensively for investigating neuronal morphology and acts as a cell type-selective fluorescent mar...

  • YN321749 Geissoschizine methyl ether 60314-89-8

    Geissoschizine methyl ether, a major indole alkaloid found inUncariahook, is a major active component of Yokukansan with psychotropic effects. Geissoschizine methyl ether is potent5-HT1Areceptoragonist.

  • YN270165 Pifithrin-α, p-Nitro, Cycl... 60477-38-5

    Pifithrin-α, p-Nitro, Cyclic (PFN-α) is cell-permeable and active-formp53inhibitor. Pifithrin-α, p-Nitro, Cyclic is one order magnitude more active than Pifithrin-α in protecting cortical neurons exposed to Etoposide (ED5...

  • YN321824 Neurotensin(8-13) 60482-95-3

    Neurotensin (8-13) is an active fragment of Neurotensin. Neurotensin(8-13) results in a decrease in cell-surface NT1 receptors (NTR1) density.

  • YN321690 Clocapramine hydrochloride hy... 60789-62-0

    Clocapramine hydrochloride hydrate is an antagonist of theD2 and 5-HT2Areceptors.

  • YN360466 Ebselen 60940-34-3

    Ebselen is a small-molecule capsid inhibitor of HIV-1 Replication with IC50 of 46.1 nM in TR-FRET assay.

  • YN360985 Ferulamide 61012-31-5

    Ferulamide is a Ferulic acid derivative isolated fromPortulaca oleracea L.with anticholinesterase activities.

  • YN373335 Licoflavone A 61153-77-3

    Licoflavone A is a flavonoid isolated from the roots ofGlycyrrhiza uralensis, inhibits protein tyrosine phosphatase-1B (PTP1B), with an IC50 of 54.5μM.

  • YN321948 β-Endorphin, human 61214-51-5

    β-Endorphin, human, a prominent endogenous peptide, existing in the hypophysis cerebri and hypothalamus, is an agonist ofopioid receptor, with preferred affinity forμ-opioid receptor and δ-opioid receptor; β-Endorphin, human exhibit...

  • YN484184 Tiopinac 61220-69-7

    Tiopinac (RS 40974), a dibenzthiepin, is an orally active and highly potent anti-inflammatory, analgesic and anti-pyretic agent.

  • YN251433 Verbascoside 61276-17-3

    Verbascoside, a phenylpropanoid glycoside from lemon verbena, has several biological properties such as anti-inflammatory, antimicrobial, antitumor, and antioxidant.

  • YN330519 Schisandrin B 61281-37-6

    Schisandrin B is the most abundant dibenzocyclooctadiene lignan present in the traditional Chinese medicinal herb Schisandra chinensis (Turcz.) Baill. It is a kind of ATR and P-gp inhibitor with high safety.

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