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Neurological Disease

Chemical structure

Cat.No.

Product Name

CAS no.

Target

  • YN1730109 Quinpirole Hydrochloride 85798-08-9

    Quinpirole Hydrochloride ((-)-LY 171555) is a high-affinity agonist ofdopamine D2/D3receptor.

  • YN361071 Rilmazafone hydrochloride 85815-37-8

    Rilmazafone hydrochloride (450191S) is a benzodiazepine (omega) lig and with sedative and hypnotic effects.

  • YN321104 Medetomidine 86347-14-0

    Medetomidine(Domtor) is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750nM for α2- and α1-adrenoceptors respectively). Medetomidine displays greater selectivity over α1-adrenoceptors than clonidi...

  • YN321106 Medetomidine hydrochloride 86347-15-1

    Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor.

  • YN321789 Corticotropin-releasing facto... 86784-80-7

    Corticotropin-releasing factor human (Human CRF) stimulates the synthesis and secretion of adrenocorticotropin in the anterior pituitary.

  • YN370784 Prolyl Endopeptidase Inhibi... 86925-97-5

    Prolyl Endopeptidase Inhibitor 1 (Boc-Pro-prolinal) is a potentprolyl endopeptidase (PEP; PE)inhibitor, with aKivalue of 15nM. Prolyl Endopeptidase Inhibitor 1 has anti-amnesic effect.

  • YN321802 Neurokinin A 86933-74-6

    Neurokinin A (Substance K), a peptide neurotransmitter of the tachykinin family, acts via theNK-2receptor. Neurokinin A acts as a major mediator in human airway and gastrointestinal tissues.

  • YN321819 Neurokinin B 86933-75-7

    Neurokinin B belongs to the tachykinin family of peptides. Neurokinin B binds a family of GPCRs-including neurokinin receptor 1 (NK1R), NK2R, and NK3R-to mediate their biological effect.

  • YN360005 Bamaluzole 87034-87-5

    Bamaluzole is a GABA receptoragonist extracted from patent WO 2012064642 A1.

  • YN320343 Ritanserin 87051-43-2

    Ritanserin (R 55667) is a highly potent, relatively selective, orally active, long acting antagonist of5-HT2receptor, with an IC50 of 0.9nM, less active on Histamine H1, Dopamine D2, Adrenergic α1, Adrenergic α2receptors.

  • YN373489 Neuromedin B 87096-84-2

    Neuromedin B (NMB) is a member of Bombesin (BN)-like peptide family in mammals.

  • YN320360 SCH-23390 maleate 87134-87-0

    SCH-23390 maleate (R-(+)-SCH-23390 maleate) is a potent and selectivedopamine D1-like receptorantagonist with Kis of 0.2nM and 0.3nM for theD1 and D5receptor, respectively. SCH-23390 maleate is a potent and high effica...

  • YN321954 Melanin Concentrating Hormo... 87218-84-6

    Melanin Concentrating Hormone, salmon is a 19-amino-acid neuropeptide initially identified in the pituitary gl and of teleost fish, which regulates food intake, energy balance, sleep state, and the cardiovascular system. Melanin-conc...

  • YN322002 Biotin-Substance P 87468-58-4

    Biotin-Substance P is the biotin tagged Substance P. Substance P (Neurokinin P) is a neuropeptide, acting as a neurotransmitter and as a neuromodulator in the CNS. The endogenous receptor for substance P isneurokinin 1 recep...

  • YN320890 Tandospirone 87760-53-0

    T and ospirone (SM-3997) is a potent and selective5-HT1Areceptor partial agonist, with a Ki of 27nM. T and ospirone can be used for the research of the central nervous system disorders and the underlying mechanisms.

  • YN370421 15-Deoxy-Δ-12,14-prostagland... 87893-55-8

    15-Deoxy-Δ-12,14-prostagl and in J2 (15d-PGJ2) is a cyclopentenone prostagl and in and a metabolite of PGD2. 15-Deoxy-Δ-12,14-prostagl and in J2 is a selectivePPARγ(EC50of 2 µM) and a covalentPPARδagonist. 15-D...

  • YN380202 Eprobemide 87940-60-1

    Eprobemide is a reversible monoamine oxidase A (MAO-A) inhibitor. Eprobemide acts as an antidepressant in Russia.

  • YN482945 Notoginsenoside Fa 88100-04-3

    Notoginsenoside Fa, a protopanaxadiol (ppd)-type saponin isolated fromP. notoginseng, could possibly activate and recover the function of degenerated brain.

  • YN372476 MDL-28170 88191-84-8

    MDL-28170 (Calpain Inhibitor III) is a potent and selective calpain inhibitor of calpain that penetrates the blood-brain barrier and inhibits brain cysteine protease activity after systemic administration. MDL-28170 is also an in...

  • YN270469 Notopterol 88206-46-6

    Notopterol is a coumarin extracted fromN. incisum. Notopterol inducesapoptosis and has antipyretic, analgesic and anti-inflammatory effects. Notopterol is used for acute myeloid leukemia (AML).

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