YN1730019 Raclopride 84225-95-6

Raclopride is adopamine D2/D3receptorantagonist, which binds toD2 and D3receptors with dissociation constants (Kis) of 1.8nM and 3.5nM, respectively, but has a very low affinity for D1 and D4receptors with Kis of 18000nM and...

YN360302 Flumazenil acid 84378-44-9

Flumazenil acid is a metabolite of Flumazenil. Flumazenil is a GABAA receptor antagonist.

YN320010 Darenzepine 84629-61-8

Darenzepine is amuscarinic receptorinhibitor extracted from patent US 20170095465 A1.

YN340281 Astragaloside VI 84687-45-6

Astragaloside VI could activateEGFR/ERKsignalling pathway to improve wound healing.

YN321946 Small Cardioactive Peptide ... 84746-43-0

Small Cardioactive Peptide B (SCPB), a neurally active peptide, stimulatesadenylate cyclaseactivity in particulate fractions of both heart and gill tissues with EC50s of 0.1 and 1.0μM, respectively.

YN482471 Rosavin 84954-92-7

Rosavin is isolated fromR. rosea, Rosavin shows antidepressant-like, adaptogenic, anxiolytic-like effects in mice model.

YN482470 Rosarin 84954-93-8

Rosarin is a cinnamyl alcohol glycoside isolated fromRhodiola rosea. Rosarin has anti-inflammatory and neuroprotectiveeffects. Rosarin supresses the expression of the proinflammatory factors iNOS, IL-1 β, and TNF- α in t...

YN320255 Proglumide hemicalcium 85068-56-0

Proglumide hemicalcium is a nonpeptide and orally activecholecystokinin (CCK)-A/B receptorsantagonist. Proglumide hemicalcium selective blocksCCK’s effects in the central nervous system (CNS). Proglumide hemicalcium has abi...

YN360565 NBI-98782 85081-18-1

NBI-98782(alpha-dihydrotetrabenazine) is a vesicular monoamine transporter (VMAT2) inhibtior with an Ki value of 0.97nM.

YN360122 Gaboxadol hydrochloride 85118-33-8

Gaboxadol hydrochloride (Lu 02-030 hydrochloride; THIP hydrochloride) is a potent agonist of the GABAA receptor and an antagonist of GABAC receptors(IC50=25μM). Gaboxadol hydrochloride displays a partial agonist effic...

YN370776 Sphingomyelin 85187-10-6

Sphingomyelin is a eukaryotic sphingolipid and one of the major constituents of cell membranes and particularly abundant in the myelin sheath that surrounds neuronal axons. Sphingomyelin plays an important role in cell processes, the ...

YN360014 SKF89976A hydrochloride 85375-15-1

SKF89976A hydrochloride is a selective GABA transporter(GAT-1) inhibitor with IC50s of 0.28μM, 137.34μM and 202.8μM for GAT-1, GAT-2 and GAT-3 in CHO cells, respectively.

YN372412 (R)-(-)-Rolipram 85416-75-7

(R)-(-)-Rolipram is the R-enantiomer of Rolipram. Rolipram is a selective inhibitor of phosphodiesterasesPDE4with IC50 of 3nM, 130nM and 240nM for PDE4A, PDE4B, and PDE4D, respectively.

YN480136 Bencianol 85443-48-7

Bencianol is a the semisynthetic flavinoid, with anti-spasmogenic activities.

YN320554 VU0238441 85511-68-8

VU0238441 is a panmuscarinic acetylcholine receptor (mAChR)positive allosteric modulator (PAM) with EC50s of 3.2μM, 2.8μM, 2.2μM, 2.1μM, >10μM for M1, M2, M3, M5 and M4, respectively.

YN340265 Curculigoside 85643-19-2

Curculigoside, a diterpenoid triepoxide, is one of the main bioactive phenolic compounds isolated from the rhizome of Curculigo orchioides Gaertn. and has potent antioxidant, anti-osteoporotic, immunomodulatory, and neuroprotective effec...

YN321455 Mirtazapine 85650-52-8

Mirtazapine is an adrenergic and seroton receptor antagonist, used to treat depression.

YN320426 Asenapine maleate 85650-56-2

Asenapine maleate is a high-affinity antagonist of serotonin, norepinephrine, dopamine and histamine receptors, used for the treatment of schizophrenia and acute mania associated with?bipolar disorder.

YN321269 Setiptiline maleate 85650-57-3

Setiptiline (MO-8282) is aserotonin receptorantagonist. Setiptiline is a tetracyclic antidepressant (TeCA) which acts as a noradrenergic and specific serotonergic antidepressant (NaSSA). Setiptiline acts as a norepinephrine re...

YN321505 Scopine hydrochloride 85700-55-6

Scopine hydrochloride (6,7-Epoxytropine hydrochloride) is the metabolite of anisodine, which is a α1-adrenergic receptor agonist and used in the treatment of acute circulatory shock.