YN370342 Nitecapone 116313-94-1

Nitecapone (OR-462) is an orally active and short-actingcatechol-O-methyltransferase (COMT)inhibitor with gastroprotective and antioxidant properties. Nitecapone (OR-462) scavenges reactive oxygen and nitric radicals and ...

YN483432 Oleuroside 116383-31-4

Oleuroside is a phenolic secoiridoid in olive. Oleuroside can protect against mitochondrial dysfunction in models of early Alzheimer's disease and brain ageing.

YN482969 Loureirin C 116384-24-8

Loureirin C, isolated from "Dragon’s blood", which is a deep red resin obtained from a variety of plant sources. The resin extracted from stems ofDracaena cochinchinensisis one such source of “dragon’s blood”, has a reputation for ...

YN380160 Duloxetine 116539-59-4

Duloxetine(LY-248686) is a potent inhibitor of serotonin (5-hydroxytryptamine, 5-HT) and noradrenaline (NE) uptake in vitro and in vivo and is 3- to 5-times more effective at inhibiting 5-HT uptake.

YN484011 Calmodulin-Dependent Protei... 116826-37-0

Calmodulin-Dependent Protein Kinase II (281-309) is a peptide of calcium/calmodulin-dependent protein kinase II (CaM-kinase II).

YN380115 (+)-Phenserine 116839-68-0

(+)-Phenserine is a novel selectivecholinesterasenoncompetitive inhibitor with an IC50 of 45.3μM.

YN482740 3'-Methoxypuerarin 117047-07-1

3'-Methoxypuerarin (3'-MOP) is an isoflavone extracted from radixpuerariaethat shows neuron protection activity.

YN250524 Etoposide phosphate 117091-64-2

Etoposide phosphate (BMY-40481) is a potentanti-cancerchemotherapy agent and a selectivetopoisomerase IIinhibitor to prevent re-ligation of DNA str and s. Etoposide phosphate is the phosphate ester prodrug of etoposide and is...

YN360178 Dehydrosoyasaponin I 117210-14-7

Dehydrosoyasaponin I (Soyasaponin Be;DHS-I), a triterpene glycoside, is a potent and reversiblecalcium-activated potassium (maxi-K) channelsactivator.

YN483766 Endothelin-3, human, mouse, r... 117399-93-6

Endothelin-3, human, mouse, rabbit, rat is a 21-amino acid vasoactive peptide that binds to G-protein-linked transmembrane receptors,ET-RA and ET-RB.

YN483850 Neuromedin U, rat 117505-80-3

Neuromedin U, rat is a 23-amino acid brain-gut peptide. Neuromedin U (NMU), through its cognate receptornMUR2 in the central nervous system, regulates several important physiological functions, including energy balance, stress res...

YN483990 Egg Laying Hormone, aplysia 117680-39-4

Egg Laying Hormone, aplysia is a neuropeptide synthesized by the bag cell neurons, which contains 36 amino acids and can stimulate egglaying and ovulation in Aplysia via electrical discharge triggering of neurons. Egg-laying hormon...

YN322012 ENS-163 phosphate 117707-51-4

ENS-163 phosphate is a selectivemuscarinic M1 receptoragonist.

YN360155 Loreclezole 117857-45-1

Loreclezole, an antiepileptic compound, is a selectiveGABAAreceptormodulator and acts as a positive allosteric modulator of β2 or β3-subunit containing receptors.

YN361056 NT 13 117928-93-5

NT 13 (TPPT) is a tetrapeptide having the amino acid sequence L-threonyl-L-prolyl-L-prolyl-L-threonine amide. NT 13 is a partial N-methyl-D-aspartate receptor (NMDAR) agonist used in the study of depression, anxiety, and...

YN360587 Rapastinel 117928-94-6

Rapastinel (GLYX-13, BV-102, TPPT-amide) is a partial agonist of N-methyl-D-aspartate receptor (NMDAR) that targeting a glycine site. Rapastinel has long-lasting antidepressant effects.

YN320118 Luzindole 117946-91-5

Luzindole (N-0774) is a selectivemelatonin receptorantagonist. Luzindole preferentially targets MT2 (Mel1b) over MT1 (Mel1a) with Ki values of 10.2 and 158nM for human MT2 and MT1, respectively. Luzindole suppresses expe...

YN320295 TIK-301 118702-11-7

TIK-301 (PD-6735) is a chlorinated melatonin derivative and a potent, high-affinity and orally activemelatonin MT1 and MT2receptorsagonist with Kis of 0.081nM and 0.042nM, respectively. TIK-301 is also a5-HT2B/5-HT...

YN360511 NBQX 118876-58-7

NBQX (FG9202, NNC 079202) is a highly selective and competitive antagonist of AMPA receptor (AMPAR) with anti-epileptic effect.

YN321951 Peptide YY (PYY), human 118997-30-1

Peptide YY (PYY) is a gut hormone that regulates appetite and inhibits pancreatic secretion. Peptide YY (PYY) can mediate its effects through theNeuropeptide Y receptors.